{"id":122421,"date":"2025-07-16T11:59:27","date_gmt":"2025-07-16T10:59:27","guid":{"rendered":"https:\/\/www.herbalreality.com\/?post_type=herb&#038;p=122421"},"modified":"2025-07-16T12:03:04","modified_gmt":"2025-07-16T11:03:04","slug":"black-pepper","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/black-pepper\/","title":{"rendered":"Black pepper"},"content":{"rendered":"","protected":false},"featured_media":122470,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_project_id":"47224","beyondwords_content_id":"8f8eae24-f6ae-45b3-bfd5-f7358d2ac7c9","beyondwords_preview_token":"69acb93c-58c2-4de5-b63c-c5e80016543b","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[],"conditions":[694,685,696,698,695,700,697],"sustainability":[1576],"sense":[17,18,16,1820],"western_action":[990,991,993,1003,1825,1007,1010,1011,1020],"chinese_action":[1046],"ayurvedic_action":[1095,1080,1072,1068,1059,1091,1079,1099,1085],"energetics_action":[1564,1498,1557,1622,1487,1546,1620,1565,1534,1379,1554,1543,1558,1560,1547,1551,1556,1497,1562,1618,1536,1550],"region":[1897],"class_list":["post-122421","herb","type-herb","status-publish","has-post-thumbnail","hentry","conditions-cardiovascular-system","conditions-digestive-system","conditions-nervous-system","conditions-reproductive-system","conditions-respiratory-system","conditions-skin","conditions-urinary-system","sustainability-green-sustainability-status","sense-aromatic","sense-bitter","sense-hot","sense-pungent","western_action-analgesic","western_action-anthelmintic","western_action-antimicrobial","western_action-carminatives","western_action-circulatory-stimulant","western_action-diaphoretic","western_action-expectorant","western_action-febrifuge","western_action-stimulant","chinese_action-warm-interior-expel-cold","ayurvedic_action-shirovirechan","ayurvedic_action-krumighna","ayurvedic_action-dipaniya","ayurvedic_action-chaksushya","ayurvedic_action-anuloma","ayurvedic_action-rasayani","ayurvedic_action-kasahara","ayurvedic_action-shula-prasamana","ayurvedic_action-mutravirechana","energetics_action-air","energetics_action-bitter","energetics_action-blood","energetics_action-circulatory","energetics_action-dry","energetics_action-dry-quality","energetics_action-eliminatory","energetics_action-food","energetics_action-heating","energetics_action-hot","energetics_action-kapha-constitution-dosha","energetics_action-light","energetics_action-muscle","energetics_action-nervous","energetics_action-penetrating","energetics_action-pitta","energetics_action-plasma","energetics_action-pungent","energetics_action-reproductive","energetics_action-respiratory","energetics_action-sweet-post-digestive-effect-vipaka","energetics_action-vata-constitution-dosha","region-ayurvedic-herbs"],"acf":{"last_reviewed":"20250709","herb_author":1215,"banner_text":"Black pepper is a warming, drying and stimulating herb","latin_name":"<i><span style=\"font-weight: 400;\">Piper nigrum<\/span><\/i>","pseudonym_name":"Maricha","family_name":"Piperaceae","herb_summary":"Named after one of the Sanskrit names of the sun, maricha, it has the same qualities as this macrocosmic source of heat and light. It is warming, drying and stimulating to the circulatory, digestive and respiratory systems. ","key_benefits":"Stimulates circulation\r\nWarms digestion\r\nReduces lung congestion","how_does_it_feel":"<span style=\"font-weight: 400;\">As soon as you taste black pepper, there is an immediate feeling of pungency, and a light, spreading nature. The feeling is due to black pepper\u2019s volatile oils stimulating receptors on the pain fibres in the lining of the mouth. The heat originates from the increase in blood flow that results from the stimulation. This increased circulation is both at the site of the stimulation and also throughout the body.<\/span>","hdif_image_1":122474,"hdif_image_2":122475,"hdif_image_3":122471,"hdif_video":"","sense":[17,18,16,1820],"what_can_i_use_it_for":"[caption id=\"attachment_122470\" align=\"alignright\" width=\"516\"]<img class=\" wp-image-122470\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum-1000x667.jpg\" alt=\"Black pepper (Piper nigrum)\" width=\"516\" height=\"344\" \/> Black pepper (<em>Piper nigrum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Black pepper is one of the most widely used culinary spices. It is valued for its distinct biting quality attributed to one of its constituents, piperine, as well as food preservation properties. It is also widely used in the herbal tradition, constituting one third of the famous Ayurvedic formula <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/trikatu\/\"><span style=\"font-weight: 400;\">trikatu<\/span><\/a><span style=\"font-weight: 400;\"> (along with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/ginger\/\"><span style=\"font-weight: 400;\">ginger<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Zingiber officinale<\/span><\/i><span style=\"font-weight: 400;\">) and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/long-pepper\/\"><span style=\"font-weight: 400;\">long pepper<\/span><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">Piper longum<\/span><\/i><span style=\"font-weight: 400;\">)). This formula is used to stimulate circulation, digestion and for lung problems accompanied by sticky mucus. <\/span><span style=\"font-weight: 400;\">In Ayurveda, black pepper is seen as more than a spice \u2014 it's a catalyst for healing, warmth, and vitality.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Many of black pepper's properties are attributed to an alkaloid constituent known as piperine. Piperine has demonstrated stimulant activity that supports poor circulation and shifts stuck congestion within the respiratory and reproductive systems. Piperine also has the ability to enhance the bioavailability of certain constituents in both conventional and non-conventional medication (1). It increases permeability and partitioning, which can promote rapid absorption from the gastrointestinal tract (GIT). This has made black pepper a valuable herb in cases of malabsorption and\/or where there is a lack of digestive metabolism. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The high essential oil content and stimulant nature of piperine also give this herb notable tonifying actions to tissues within the reproductive and respiratory systems, improving their strength and resistance. The pungent constituents within this herb are effective as anthelmintics, targeting gastrointestinal infections (1).<\/span>","into_the_heart_of":"[caption id=\"attachment_122475\" align=\"alignright\" width=\"504\"]<img class=\" wp-image-122475\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114802\/Black-pepper-plant-Piper-nigrum-1000x667.jpg\" alt=\"Black pepper (Piper nigrum)\" width=\"504\" height=\"336\" \/> Black pepper (<em>Piper nigrum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">This parasitic creeper grows up host plants and thrives in the humid climates of southwest India and Sri Lanka. The fruit is first green, then red, then yellow and finally goes black on drying. Black pepper is powerfully heating and penetrating, making it excellent for addressing debility and nervous exhaustion of <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/ayurvedic-herbal-medicine\/ayurvedic-herbal-glossary\/\"><i><span style=\"font-weight: 400;\">vata dosha<\/span><\/i><span style=\"font-weight: 400;\"> and lethargy of <\/span><i><span style=\"font-weight: 400;\">kapha dosha.<\/span><\/i><\/a><i><span style=\"font-weight: 400;\">\u00a0<\/span><\/i>\r\n\r\n<span style=\"font-weight: 400;\">It acts as a rejuvenative (<\/span><i><span style=\"font-weight: 400;\">rasayana<\/span><\/i><span style=\"font-weight: 400;\">) for the respiratory channel, clearing sticky, white mucus and relieving congestion, <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/cough\/\"><span style=\"font-weight: 400;\">cough<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/asthma\/\"><span style=\"font-weight: 400;\">asthma<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/bronchitis\/\"><span style=\"font-weight: 400;\">bronchitis<\/span><\/a><span style=\"font-weight: 400;\">, pneumonia and sore throats (3).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It clears undigested matter (<\/span><i><span style=\"font-weight: 400;\">ama<\/span><\/i><span style=\"font-weight: 400;\">) from the lymphatic tissue, thereby resolving low and chronic fevers associated with <\/span><i><span style=\"font-weight: 400;\">kapha dosha<\/span><\/i><span style=\"font-weight: 400;\">. It stimulates blood flow, relieves uterine stagnation and menstrual issues. Being sharp and hot, it increases the digestive fire (<\/span><i><span style=\"font-weight: 400;\">agni<\/span><\/i><span style=\"font-weight: 400;\">), so it helps with all <\/span><i><span style=\"font-weight: 400;\">vata <\/span><\/i><span style=\"font-weight: 400;\">and <\/span><i><span style=\"font-weight: 400;\">kapha dosha<\/span><\/i><span style=\"font-weight: 400;\"> digestive problems due to excess cold and damp, as well as anorexia, colic, flatulence, bloating and sluggishness. Black pepper burns <\/span><i><span style=\"font-weight: 400;\">ama<\/span><\/i><span style=\"font-weight: 400;\"> in the gut, clearing worms and parasites, stimulating the liver and pancreatic function. It stimulates sweating and purifies the skin, so is helpful in skin diseases. It is also useful for oral abscesses and tooth decay.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Its stimulating quality is very powerful and this rajasic quality must be balanced with other sweet herbs or with honey.<\/span>","tradtional_uses":"[caption id=\"attachment_122471\" align=\"alignright\" width=\"518\"]<img class=\" wp-image-122471\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114753\/Black-pepper-corns-Piper-nigrum-1000x667.jpg\" alt=\"Black pepper (Piper nigrum)\" width=\"518\" height=\"345\" \/> Black pepper (<em>Piper nigrum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Black pepper, often called the \u201cKing of Spices\u201d, has been revered in both Ayurveda and traditional Chinese medicine (TCM) for thousands of years \u2014 not just for its flavour, but for its potent healing properties.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In Ayurveda, its key use is to stimulate the digestive fire (<\/span><i><span style=\"font-weight: 400;\">agni<\/span><\/i><span style=\"font-weight: 400;\">), enhancing appetite and nutrient absorption while reducing bloating and gas. Its hot, sharp qualities stimulate salivation.. It clears the deposits of <\/span><i><span style=\"font-weight: 400;\">kapha<\/span><\/i><span style=\"font-weight: 400;\"> on the tongue and chest, stimulates the liver as well as other digestive fluids. It is the ideal herb for anorexia, indigestion, liver dysfunction and colic. It is also valued for detoxification, where it is used in formulas like <\/span><i><span style=\"font-weight: 400;\">trikatu<\/span><\/i><span style=\"font-weight: 400;\"> (with ginger and long pepper), to help eliminate toxins (<\/span><i><span style=\"font-weight: 400;\">ama<\/span><\/i><span style=\"font-weight: 400;\">) and support metabolism.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">When it comes to respiratory support, black pepper is effective\u00a0 in reversing sluggishness of the <\/span><i><span style=\"font-weight: 400;\">pranav\u0101ha srotas<\/span><\/i><span style=\"font-weight: 400;\"> (respiratory channel) and reducing mucus secretions. Its pungency helps clear mucus from the lungs and sinuses, making it a go-to for colds and coughs. It is often traditionally combined with honey to dry moisture and excessive secretions, and help counter its heat. It is also a stimulant for the circulatory system, gradually removing blockages in the small capillaries and supporting blood flow.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">For the urinary system, black pepper ameliorates urinary disorders by reducing the viscosity of phlegm and supporting its removal. It also increases the flow of urine by stimulating the blood vessels in the kidneys. It has a similar stimulating action in the reproductive system, useful in menstrual issues and impotency.\u00a0 It also has a long history of external use in Ayurveda on inflamed skin when mixed with oil or used as a poultice (2). <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Black pepper is used externally in the form of paste and cream since the time of <\/span><i><span style=\"font-weight: 400;\">Charaka Samhita <\/span><\/i><span style=\"font-weight: 400;\">in the\u00a0 2<\/span><span style=\"font-weight: 400;\">nd<\/span><span style=\"font-weight: 400;\"> century BC (<\/span><i><span style=\"font-weight: 400;\">Charaka Sutrasthana<\/span><\/i><span style=\"font-weight: 400;\"> 3\/12).\u00a0 For toothache, teeth were brushed with powdered pepper, or a decoction was used for gargling. In comatose patients, inhalation of black pepper was also given. Black pepper oil is used in traditional <\/span><i><span style=\"font-weight: 400;\">abhyanga<\/span><\/i><span style=\"font-weight: 400;\"> massage for its warming, anti-inflammatory effects.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Ayurveda traditionally uses small doses of black pepper to stimulate the action of other herbs, due to its ability to open up the channels of the body. It facilitates opening of even the narrow channels, encouraging the removal of deep seated <\/span><i><span style=\"font-weight: 400;\">kapha dosha<\/span><\/i><span style=\"font-weight: 400;\">. Because of this effect, it has found a place in <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/trikatu\/\"><i><span style=\"font-weight: 400;\">trikatu<\/span><\/i><\/a><i><span style=\"font-weight: 400;\">,<\/span><\/i><span style=\"font-weight: 400;\"> a well respected Ayurvedic formulation.\u00a0<\/span>","what_practioners_say":"<span style=\"font-weight: 400;\"><img class=\" wp-image-6364 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2022\/02\/21124321\/Subcategory-Conditions-digestive-system-600x600.jpg\" alt=\"Digestive system\" width=\"381\" height=\"381\" \/>Black pepper may be usefully applied for a range of digestive, circulatory and respiratory conditions. The modern practitioner can be guided by traditional wisdom and use black pepper in a variety of cases, particularly when symptoms are made worse by cold and damp conditions and seem to be relieved by heat and dryness (4).<\/span>\r\n<h3>Digestive system<\/h3>\r\n<span style=\"font-weight: 400;\">Black pepper is useful to support low appetite, sluggish digestion, abdominal pain, toxin excretion and borborygmus. Its hot and penetrating qualities help stimulate the digestive fire (<\/span><i><span style=\"font-weight: 400;\">agni<\/span><\/i><span style=\"font-weight: 400;\">) as they increase enzymatic secretions. This helps to enhance absorption of nutrients and reduces any lingering undigested matter (<\/span><i><span style=\"font-weight: 400;\">ama<\/span><\/i><span style=\"font-weight: 400;\">). Its affinity for the eliminatory system, along with antiparasitic qualities, helps to expel parasites.<\/span>\r\n<h3>Endocrine system<\/h3>\r\n<span style=\"font-weight: 400;\">As black pepper contains chromium, a component of glucose tolerance factor, it is a valuable plant in diabetes treatment. It normalises the fat tissue and prevents ama overflowing into the pancreas and urine.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Additionally, 86 overweight people taking a supplement containing piperine and other compounds for eight weeks experienced significant improvements in insulin sensitivity,\u00a0 a measure of how well the hormone insulin removes glucose from the bloodstream (5). However, it\u2019s unclear whether the same effects would occur with black pepper alone, as a combination of many active plant compounds was used in this study.<\/span>\r\n<h3>Respiratory system<\/h3>\r\n<span style=\"font-weight: 400;\">Black pepper is specific for cold, wet, damp <\/span><i><span style=\"font-weight: 400;\">kapha<\/span><\/i><span style=\"font-weight: 400;\"> conditions in the respiratory channel with white sticky mucus and a productive cough, so is indicated for <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/asthma\/\"><span style=\"font-weight: 400;\">asthma<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/bronchitis\/\"><span style=\"font-weight: 400;\">bronchitis<\/span><\/a><span style=\"font-weight: 400;\">, pneumonia and sore throats. Black pepper infused with oil or ghee, applied to the nose, can be a wonderful decongestant for blocked sinuses.<\/span>\r\n<h3>Immune system<\/h3>\r\n<span style=\"font-weight: 400;\">Black pepper can help to raise the temperature to make the environment inhospitable to pathogens, and induce a sweat to release the misplaced <\/span><i><span style=\"font-weight: 400;\">agni <\/span><\/i><span style=\"font-weight: 400;\">that has moved from the stomach to the plasma tissues. It clears undigested matter (<\/span><i><span style=\"font-weight: 400;\">ama<\/span><\/i><span style=\"font-weight: 400;\">) from the lymph. It can be used as part of a treatment for intermittent fevers such as malaria when combined with bitter, cooling herbs.\u00a0<\/span>\r\n<h3>Cardiovascular system<\/h3>\r\n<span style=\"font-weight: 400;\">Pepper stimulates microcirculation in the capillaries, useful in cirrhosis, hepatitis and skin diabesity signs of stagnant blood, e.g., red or purple patches and chronic lesions. It can also help with cold congestion in the uterus in cases of dysmenorrhoea and amenorrhoea. An external application of the essential oil in the form of a poultice can help relieve neuralgic and arthritic pain with cold swellings. This can also be used to draw out boils and abscesses. It can also be used as a decoction for sore throats. <\/span>","research":"[caption id=\"attachment_122473\" align=\"alignright\" width=\"516\"]<img class=\" wp-image-122473\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114758\/Black-pepper-fruit-Piper-nigrum-1000x667.jpg\" alt=\"Black pepper (Piper nigrum)\" width=\"516\" height=\"344\" \/> Black pepper (<em>Piper nigrum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Research has provided compelling support for many of black pepper\u2019s traditional Ayurvedic uses, mainly looking at its key bioactive compound<\/span><b>, <\/b><span style=\"font-weight: 400;\">piperine. However, despite these promising findings, more studies in humans are needed to better understand the exact actions of black pepper.\u00a0<\/span>\r\n<h3>A systematic review on black pepper: From folk uses to pharmacological applications<\/h3>\r\n<span style=\"font-weight: 400;\">A review attempted to systematically review scientific data on the traditional uses, phytochemical composition and pharmacological properties of black pepper (6). Antimicrobial activity was recorded against a wide range of pathogens. Studies also reported its antioxidant effects and improvement of antioxidant enzymes <\/span><i><span style=\"font-weight: 400;\">in vivo<\/span><\/i><span style=\"font-weight: 400;\">. It also exhibited an anticancer effect against a number of cell lines from breast, colon, cervical and prostate through different mechanisms, including cytotoxicity, apoptosis, autophagy and interference with signalling pathways. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Its antidiabetic property has also been confirmed <\/span><i><span style=\"font-weight: 400;\">in vivo<\/span><\/i><span style=\"font-weight: 400;\"> as well as hypolipidemic activity as evidenced by a decrease in the level of cholesterol, triglycerides, and low-density lipoprotein and an increase in high-density lipoprotein. Black pepper also has anti-inflammatory, analgesic, anticonvulsant, and neuroprotective effects. The major bioactive compound is piperine although other compounds are also present including piperic acid, piperlonguminine, pellitorine, piperolein B, piperamide, piperettine, and kusunokinin, which also showed biological potency.\u00a0 <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The review looked at 60 pharmacological studies conducted <\/span><i><span style=\"font-weight: 400;\">in vitro,<\/span><\/i><span style=\"font-weight: 400;\"> with only 21 <\/span><i><span style=\"font-weight: 400;\">in vivo<\/span><\/i><span style=\"font-weight: 400;\"> and 1 clinical trial. Hence, more <\/span><i><span style=\"font-weight: 400;\">in vivo<\/span><\/i><span style=\"font-weight: 400;\"> experiments and clinical trials would be beneficial to better understand black pepper's <\/span><i><span style=\"font-weight: 400;\">\"<\/span><\/i><span style=\"font-weight: 400;\">panoply of bioactive compounds with potential nutraceutical and pharmaceutical applications\u201d<\/span><i><span style=\"font-weight: 400;\"> (6).<\/span><\/i>\r\n<h3>Permeability characteristics of piperine on oral absorption: n active alkaloid from peppers and a bioavailability enhancer<\/h3>\r\n<span style=\"font-weight: 400;\">Piperine is the pungent alkaloid present in both black pepper and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/long-pepper\/\"><span style=\"font-weight: 400;\">long pepper<\/span><\/a><span style=\"font-weight: 400;\">. It is known to significantly increase the absorption of nutrients and herbal compounds like <\/span><a href=\"https:\/\/www.herbalreality.com\/?s=turmeric\"><span style=\"font-weight: 400;\">curcumin<\/span><\/a><span style=\"font-weight: 400;\">, which supports its traditional role in Ayurvedic formulations like <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/trikatu\/\"><i><span style=\"font-weight: 400;\">trikatu<\/span><\/i><\/a><span style=\"font-weight: 400;\"> (<\/span><i><span style=\"font-weight: 400;\">7)<\/span><\/i><span style=\"font-weight: 400;\">. One <\/span><i><span style=\"font-weight: 400;\">in vitro <\/span><\/i><span style=\"font-weight: 400;\">study explored how it enhances the bioavailability of various structurally and therapeutically diverse drugs, looking specifically at oral absorption using intestinal sacs as an experimental model (8).<\/span>\r\n\r\n<span style=\"font-weight: 400;\"> Piperine was found to be highly lipophilic in nature, being absorbed through the transcellular pathway. The study's findings suggest piperine is absorbed quickly across the intestinal barrier and may even modulate membrane dynamics, enhancing permeability across the barriers.<\/span>\r\n<h3>Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice<\/h3>\r\n<span style=\"font-weight: 400;\">Chronic inflammation may be an underlying factor in many conditions, with many studies suggesting black pepper may effectively reduce inflammation (9)<\/span><i><span style=\"font-weight: 400;\">. <\/span><\/i><span style=\"font-weight: 400;\">For example, in studies in rats with arthritis, treatment with piperine resulted in less joint swelling and fewer blood markers of inflammation (10,11). In mouse studies, piperine suppressed inflammation in the airways caused by asthma (12) and seasonal allergies (13). <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Allergic rhinitis is a global health problem that affects a large portion of the population. As piperine has been shown to have anti-inflammatory, anti-histaminic, and immunomodulatory activities, this study sought to explore its antiallergic profile in mice. Piperine was shown to have a significant dose-dependent protection with respect to nasal rubbing, redness of the nose, and sneezing, and to reduce histamine.\u00a0 <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The study concluded that piperine acts by mast cell-stabilising activity, exhibiting immunomodulatory and anti-inflammatory activity, thereby providing an effective treatment for allergic rhinitis.\u00a0<\/span>\r\n<h3>Evaluation of analgesic properties of\u00a0<i>Piper nigrum<\/i>\u00a0essential oil<\/h3>\r\n<span style=\"font-weight: 400;\">Studies have indicated that the essential oil of black pepper has anti-inflammatory effects. In particular, linalool, a monoterpene, is one component of black pepper essential oil that has demonstrated analgesic properties in preclinical studies. However, little is known about black pepper essential oil beyond these effects, so a randomised, double-blind, placebo-controlled trial sought to evaluate the analgesic properties of black pepper essential oil in patients experiencing pain (14). <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Fifty-four patients were randomly divided into two different groups and provided identical-looking vials containing either the experimental oil or the placebo oil. Patients in group A inhaled the black pepper essential oil, while patients in group B inhaled sesame oil, both for 15 minutes. Before and after the treatment, patients were provided a questionnaire where they indicated the intensity and location of the pain. There was a significant difference found between the two groups. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Consistent with preliminary research on the volatile constituents of black pepper, the authors found that inhalation of black pepper essential oil resulted in a significantly lower pain intensity score than the placebo. Due to the small sample size, pain region variability, and unbalanced gender of this trial, more studies are needed to assess differences between gender and pain regions. The results of this study indicate that black pepper essential oil may be a valuable resource for pain management.<\/span>","did_you_know":"<span style=\"font-weight: 400;\">Black pepper is traditionally used in India to reduce the <\/span><i><span style=\"font-weight: 400;\">kapha<\/span><\/i><span style=\"font-weight: 400;\"> aggravating effect of sweet fruit juices. It is also used in post-partum care and is included in<\/span> <span style=\"font-weight: 400;\">herbal remedies given to the new mother. Black pepper is added to control <\/span><i><span style=\"font-weight: 400;\">vata dosha<\/span><\/i><span style=\"font-weight: 400;\"> aggravation that naturally occurs post-delivery.<\/span>","additional_information_right":{"illustration":122482},"additional_information_left":{"botany":"<span style=\"font-weight: 400;\"><em>Piper nigrum<\/em> is a perennial vine. The leaves are simple, alternate, oval, leathery and the upper surface is dark green and whitish green below. The flowers are greenish yellow and arranged in a spiral along the spine. Fruit is an oval drupe, green in colour, then becomes yellow to red and finally turns a black colour. The fruit contains a seed (19).<\/span>","common_names":"<ul>\r\n \t<li><span style=\"font-weight: 400;\">Common pepper,<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Pepper<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Maricha (Sanskrit)<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Kalimirch (Hindi)<\/span><\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400;\">Black pepper has been safely used as a food for many centuries, with few adverse reports in daily cuisine, clinical practice or in clinical trials at a low dose.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">As it is heating, no more than 5 g should be given daily over long time periods.\u00a0 A low dose such as those found in food is safe for long-term use. The piperine content of black pepper , when used as an isolated ingredient, has been associated with enhancing blood levels of certain medications e.g., propranolol, theorphylline, refampicin. It may also inhibit drug metabolism in the liver if used over long periods at high doses; hence, all patients taking drugs that are metabolised in the liver must be carefully monitored. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">In its whole form, it also increases short-term bioavailability by increasing nutrient absorption and reducing blood levels of medication (15).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Based on centuries of safe use as a food by pregnant women, black pepper appears to be safe for use during pregnancy when taken as a culinary spice; however, it should be avoided in high doses as, in theory, it may have abortifacient effects (2,4,16). <\/span>\r\n\r\n<span style=\"font-weight: 400;\">There is limited research as to effects in high doses though one study looked at a culinary dose during breast feeding. \u00a0Thirteen nursing mothers who were nursing their infants were served a curry dish that contained an average piperine concentration of 264 nmol\/gram (75 mcg\/gram) in curry sauce. The peak piperine concentration in milk of 31.2 nM (8.9 mcg\/L) occurred at one hour after the meal in these mothers with a low basal piperine concentration in milk. The authors assumed the concentration of piperine was too low for conscious detection by the nursing infant, but that it could contribute to a sensory desensitisation toward pungency in later life (17).\u00a0<\/span>","interactions":"<span style=\"font-weight: 400;\">Caution with sedatives, benzopdiazepines, barbiturates. Black pepper increases the absorption and action of medications and analgesic activity of diclofenac and pentazocine (2,4).<\/span>","contraindications":"<span style=\"font-weight: 400;\">It can irritate mucous membranes. Avoid in hyperacidity and dryness. Black pepper also aggravates <\/span><i><span style=\"font-weight: 400;\">vata dosha<\/span><\/i><span style=\"font-weight: 400;\"> in excess (3,4). <\/span>","preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Powder<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decoction<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Poultice\/ external paste<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Essential oil<\/span><\/li>\r\n<\/ul>","dosage":"<ul>\r\n \t<li><b>Tincture (ratio 1:5| 70%):<\/b> 1\u20132 ml daily<\/li>\r\n \t<li><b>Dried: <\/b><span>1\u20133 g a day<\/span><\/li>\r\n \t<li>With ghee \/ honey for <i><span>kapha <\/span><\/i><span>congestion in <\/span><i><span>pranavaha srotas <\/span><\/i><span>(4)<\/span><\/li>\r\n<\/ul>","constituents":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Volatile oils:<\/b><span style=\"font-weight: 400;\">\u00a0 Sabinene, camphene, limonene, myrcene, piperonal, pinene, myrcene, carene<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Monoterpene derivatives<\/b><span style=\"font-weight: 400;\">: Borneol, carvone, carvacrol, cineol, linalool, caryophyllene, humulene, bisabolone and caryophyllene<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Alkaloids:<\/b><span style=\"font-weight: 400;\"> Piperine, piperdine, piperanine, chavicine and piperettine<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><strong>Chromium oxide and ketone<\/strong><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Phenylethers:<\/b><span> Eugenol, myristicin, safrole (18)<\/span><\/li>\r\n<\/ul>","plant_part_used":"Fruit"},"habitat":"<span style=\"font-weight: 400;\">Cultivated in India, Sri Lanka, Malaysia, Indonesia, West Africa and Madagascar. <\/span><span style=\"font-weight: 400;\">\r\n<\/span><span style=\"font-weight: 400;\">In India specifically, it can be found growing on the hills of south-western India. Cultivated in Assam, Karnataka, Maharashtra and Kerala (19)<\/span><b>.<\/b>","sustainability":"[caption id=\"attachment_97187\" align=\"alignright\" width=\"349\"]<a href=\"https:\/\/www.herbalreality.com\/herbalism\/sustainability-social-welfare\/herb-species-sustainability-guide\/\"><img class=\" wp-image-97187\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/05\/25101030\/Green-sustainability-status-1000x1000.png\" alt=\"Green Sustainability Status\" width=\"349\" height=\"349\" \/><\/a> Not currently on risk lists but complete data may be missing on the status of the species. Read more in our <a href=\"https:\/\/www.herbalreality.com\/herbalism\/sustainability-social-welfare\/herb-species-sustainability-guide\/\">sustainability guide<\/a>.[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Black pepper is one of the most widely used and traded spices in the world. However, its cultivation can have negative environmental impacts if not managed sustainably (20).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Black pepper cultivation typically involves the clearing of land for planting, the use of chemical fertilisers and pesticides, and the intensive use of water. These practices can lead to deforestation, soil erosion, water pollution, and loss of biodiversity. Additionally, the carbon footprint of black pepper farming can be significant due to the use of fossil fuels for machinery and transportation. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">To reduce the environmental impact of black pepper farming, farmers can adopt sustainable practices such as agroforestry, organic farming, and water conservation techniques. Agroforestry involves planting trees alongside black pepper vines, which can help reduce soil erosion, provide habitat for wildlife, and sequester carbon dioxide (21).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Habitat loss and over-harvesting from the wild are two of the biggest threats faced by medicinal plant species. There are an increasing number of well-known herbal medicines at risk of extinction. We must, therefore, ensure that we source our medicines with sustainability in mind.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The herb supplement industry is growing at a rapid rate and until recent years a vast majority of medicinal plant produce in global trade was of unknown origin. There are some very real and urgent issues surrounding sustainability in the herb industry. These include environmental factors that affect the medicinal viability of herbs, the safety of the habitats that they are taken from, as well as the welfare of workers in the trade.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The botanical supply chain efforts for improved visibility (transparency and traceability) into verifiably sustainable production sites around the world is now certificated through the emergence of credible international voluntary sustainability standards (VSS).<\/span><span style=\"font-weight: 400;\">\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality &amp; safety: What to know before you buy<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"<span style=\"font-weight: 400;\">Herbal medicines are often very safe to take; however, their safety and efficacy can be jeopardised by quality issues. So, it is important to buy herbal medicines from a reputable supplier, from sources known to test their herbs to ensure there is no contamination, adulteration or substitution with incorrect plant matter, as well as ensuring that recognised marker compounds are at appropriate levels in the herbs.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Some important quality assurances to look for are certified organic labelling, the correct scientific\/botanical name, and the availability of information from the supplier about ingredient origins. A supplier should be able to tell you where the herbs have come from, what contaminants are not in the herb, and what the primary compounds are.<\/span>","how_to_grow":"Black pepper will thrive in warm and humid climates, ideally between 20\u201330\u00b0C and will not grow in temperatures lower than 21\u00b0C. To grow black pepper from seed, soak the seeds beforehand to soften them and increase chances of germination. Sow the seeds in nutrient rich compost, germination will take between 2\u20134 weeks. Keep the soil moist but not waterlogged and ensure good drainage when they are planted out. Plant the seedlings out once they have reached 15 cm and provide a support structure such as a trellis or stake as it is a climbing vine (22).","recipe":"[caption id=\"attachment_122479\" align=\"alignright\" width=\"513\"]<img class=\" wp-image-122479\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16115136\/Black-pepper-tea-Piper-nigrum-1000x667.jpg\" alt=\"Black pepper tea (Piper nigrum)\" width=\"513\" height=\"342\" \/> Black pepper tea (<em>Piper nigrum<\/em>)[\/caption]\r\n<h3>Weight-balancing tea<\/h3>\r\n<span style=\"font-weight: 400;\">When our digestive fire is low it cannot transform food into nourishing energy.<\/span><span style=\"font-weight: 400;\">\r\n<\/span><span style=\"font-weight: 400;\">Instead, food can get stored as fat, starting a vicious cycle where digestion becomes weaker and weaker, leading to steady weight gain. This tea stimulates metabolism to help you find your natural and balanced weight. It's a fiery one.<\/span>\r\n<h4>Ingredients<\/h4>\r\n<ul>\r\n \t<li><span style=\"font-weight: 400;\">Cinnamon bark 4 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Ginger root powder 2 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Orange peel 2 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Green tea 2 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Turmeric root powder 1 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Black pepper 1 g<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Orange essential oil, one drop per cup (we recommend using an essential oil that is specific for internal use)<\/span><\/li>\r\n<\/ul>\r\n<h4>How to make a black pepper tea<\/h4>\r\n<span style=\"font-weight: 400;\">This will serve 2\u20133 cups of digestion-enhancing, weight-balancing tea that works together with lots of exercise.\u00a0<\/span>\r\n<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Put all of the ingredients in a pot (except for the orange essential oil).<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Add 500 ml\/18 fl oz freshly boiled filtered water.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Leave to steep for 10\u201315 minutes, then strain.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Add one drop of orange essential oil to each cup.<\/span><\/li>\r\n<\/ul>\r\n<span style=\"font-weight: 400;\">Recipe from <\/span><span style=\"font-weight: 400;\"><em>Cleanse, Nurture, Restore<\/em><\/span><span style=\"font-weight: 400;\">\u00a0by Sebastian Pole<\/span>","references":"<ol>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Srinivasan K. Black pepper and its pungent principle-piperine: a review of diverse physiological effects. <\/span><i><span style=\"font-weight: 400;\">Crit Rev Food Sci Nutr<\/span><\/i><span style=\"font-weight: 400;\">. 2007;47(8):735-748. <\/span><a href=\"https:\/\/doi.org\/10.1080\/10408390601062054\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1080\/10408390601062054<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pole S. <\/span><i><span style=\"font-weight: 400;\">Ayurvedic Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2013:237.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gogte VM. <\/span><i><span style=\"font-weight: 400;\">Ayurvedic Pharmacology and Therapeutic Uses of Medicinal Plants<\/span><\/i><span style=\"font-weight: 400;\">. 1982:460.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">McIntyre A, Boudin B. <\/span><i><span style=\"font-weight: 400;\">Dispensing with Tradition<\/span><\/i><span style=\"font-weight: 400;\">. 2012:218. <\/span><i><span style=\"font-weight: 400;\">(Note: Publication date corrected from 21012 to 2012)<\/span><\/i><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Rondanelli M, Opizzi A, Perna S, et al. Improvement in insulin resistance and favourable changes in plasma inflammatory adipokines after weight loss associated with two months\u2019 consumption of a combination of bioactive food ingredients in overweight subjects. <\/span><i><span style=\"font-weight: 400;\">Endocrine<\/span><\/i><span style=\"font-weight: 400;\">. 2013;44(2):391-401. <\/span><a href=\"https:\/\/doi.org\/10.1007\/s12020-012-9863-0\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1007\/s12020-012-9863-0<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Takooree H, Aumeeruddy MZ, Rengasamy KR, et al. A systematic review on black pepper (Piper nigrum L.): from folk uses to pharmacological applications. <\/span><i><span style=\"font-weight: 400;\">Crit Rev Food Sci Nutr<\/span><\/i><span style=\"font-weight: 400;\">. 2019;59(sup1):S210-S243. <\/span><a href=\"https:\/\/doi.org\/10.1080\/10408398.2019.1565489\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1080\/10408398.2019.1565489<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Stojanovi\u0107-Radi\u0107 Z, Pej\u010di\u0107 M, Dimitrijevi\u0107 M, et al. Piperine\u2014a major principle of black pepper: a review of its bioactivity and studies. <\/span><i><span style=\"font-weight: 400;\">Appl Sci<\/span><\/i><span style=\"font-weight: 400;\">. 2019;9(20):4270. <\/span><a href=\"https:\/\/doi.org\/10.3390\/app9204270\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.3390\/app9204270<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Khajuria A, Zutshi U, Bedi KL. Permeability characteristics of piperine on oral absorption\u2014an active alkaloid from peppers and a bioavailability enhancer. <\/span><i><span style=\"font-weight: 400;\">Indian J Exp Biol<\/span><\/i><span style=\"font-weight: 400;\">. 1998;36(1):46-50.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kunnumakkara AB, Sailo BL, Banik K, et al. Chronic diseases, inflammation, and spices: how are they linked? <\/span><i><span style=\"font-weight: 400;\">J Transl Med<\/span><\/i><span style=\"font-weight: 400;\">. 2018;16:14. <\/span><a href=\"https:\/\/doi.org\/10.1186\/s12967-018-1381-2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1186\/s12967-018-1381-2<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bang JS, Oh DH, Choi HM, et al. Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1\u03b2-stimulated fibroblast-like synoviocytes and in rat arthritis models. <\/span><i><span style=\"font-weight: 400;\">Arthritis Res Ther<\/span><\/i><span style=\"font-weight: 400;\">. 2009;11(2):R49. <\/span><a href=\"https:\/\/doi.org\/10.1186\/ar2662\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1186\/ar2662<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Umar S, Sarwar AHMG, Umar K, et al. Piperine ameliorates oxidative stress, inflammation and histological outcome in collagen induced arthritis. <\/span><i><span style=\"font-weight: 400;\">Cell Immunol<\/span><\/i><span style=\"font-weight: 400;\">. 2013;284(1-2):51-59. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.cellimm.2013.07.004\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.cellimm.2013.07.004\u00a0<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kim SH, Lee YC. Piperine inhibits eosinophil infiltration and airway hyperresponsiveness by suppressing T cell activity and Th2 cytokine production in the ovalbumin-induced asthma model. <\/span><i><span style=\"font-weight: 400;\">J Pharm Pharmacol<\/span><\/i><span style=\"font-weight: 400;\">. 2009;61(3):353-359. <\/span><a href=\"https:\/\/doi.org\/10.1211\/jpp\/61.03.0010\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1211\/jpp\/61.03.0010<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aswar U, Shintre S, Chepurwar S, Aswar M. Antiallergic effect of piperine on ovalbumin-induced allergic rhinitis in mice. <\/span><i><span style=\"font-weight: 400;\">Pharm Biol<\/span><\/i><span style=\"font-weight: 400;\">. 2015;53(9):1358-1366. <\/span><a href=\"https:\/\/doi.org\/10.3109\/13880209.2014.982299\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.3109\/13880209.2014.982299\u00a0<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Costa R, Machado J, Abreu C. Evaluation of analgesic properties of Piper nigrum essential oil: a randomized, double-blind, placebo-controlled study. <\/span><i><span style=\"font-weight: 400;\">World J Tradit Chin Med<\/span><\/i><span style=\"font-weight: 400;\">. 2016;2(2):60-64. <\/span><i><span style=\"font-weight: 400;\">(DOI not currently available)<\/span><\/i><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ren T, Zuo Z. Role of piperine in CNS diseases: pharmacodynamics, pharmacokinetics and drug interactions. <\/span><i><span style=\"font-weight: 400;\">Expert Opin Drug Metab Toxicol<\/span><\/i><span style=\"font-weight: 400;\">. 2019;15(10):849-867. <\/span><a href=\"https:\/\/doi.org\/10.3109\/13880209.2014.982299\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1080\/17425255.2019.1672658<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Natural Medicines Database. Black pepper. Therapeuticresearch.com. Published 2025. Accessed July 9, 2025. <\/span><a href=\"https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/Black-Pepper\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/naturalmedicines.therapeuticresearch.com\/Data\/ProMonographs\/Black-Pepper<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Drugs and Lactation Database (LactMed\u00ae) [Internet]. Bethesda, MD: National Institute of Child Health and Human Development; 2006\u2013. Black Pepper. Updated January 15, 2025. Available from: <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK579035\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK579035\/<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ashokkumar K, Murugan M, Dhanya MK, Pandian A, Warkentin TD. Phytochemistry and therapeutic potential of black pepper [Piper nigrum (L.)] essential oil and piperine: a review. <\/span><i><span style=\"font-weight: 400;\">Clin Phytosci<\/span><\/i><span style=\"font-weight: 400;\">. 2021;7(1):23. <\/span><a href=\"https:\/\/doi.org\/10.1186\/s40816-021-00292-2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1186\/s40816-021-00292-2<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Editors of Encyclopaedia Britannica. Black pepper | Plant, Cultivation, &amp; Description. In: <\/span><i><span style=\"font-weight: 400;\">Encyclopaedia Britannica<\/span><\/i><span style=\"font-weight: 400;\">. 2020. <\/span><a href=\"https:\/\/www.britannica.com\/plant\/black-pepper-plant\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.britannica.com\/plant\/black-pepper-plant<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ess Team. Sustainability in black pepper farming: reducing environmental impact and enhancing soil health. Published March 17, 2025. <\/span><i><span style=\"font-weight: 400;\">(Additional publication details not available.)<\/span><\/i><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Vernick D. Sustainable pepper farming supports people and nature in Malaysian Borneo. <\/span><i><span style=\"font-weight: 400;\">World Wildlife Fund<\/span><\/i><span style=\"font-weight: 400;\">. Published November 17, 2020. <\/span><a href=\"https:\/\/www.worldwildlife.org\/stories\/sustainable-pepper-farming-supports-people-and-nature-in-malaysian-borneo\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.worldwildlife.org\/stories\/sustainable-pepper-farming-supports-people-and-nature-in-malaysian-borneo<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gardening Know How. Black peppercorn. Published 2025. <\/span><a href=\"https:\/\/www.gardeningknowhow.com\/edible\/herbs\/peppercorn\/how-to-grow-peppercorns.htm\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.gardeningknowhow.com\/edible\/herbs\/peppercorn\/how-to-grow-peppercorns.htm<\/span><\/a><\/li>\r\n<\/ol>","related_condition":[6212,3375],"related_herb":[2016,1965],"related_article":[2039,2381],"herb_overview_content_one":"","herb_overview_content_two":"","herb_overview_content_three":"","herb_overview_content_four":"","herb_overview_content_five":"","herb_overview_content_six":"","herb_overview_content_seven":"","herb_overview_content_eight":"","botany":"","botanical_description":"","botanical_image":null,"common_names":"","herbal_preperation_image":null,"preparation":"","plant_part_used":"","dosage":"","constituents":"","recipe_image":null,"safety_post":null,"safety":"","interactions":"","contraindications":"","sustainability_image_one":null,"sustainability_image_two":null,"faqs":null,"not_suitable_for":[]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum.jpg",2400,1600,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum-1000x667.jpg",1000,667,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum-1300x867.jpg",580,387,true],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum-1600x800.jpg",1600,800,true],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/07\/16114751\/Black-pepper-Piper-nigrum.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 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