{"id":13150,"date":"2024-07-26T09:25:16","date_gmt":"2024-07-26T08:25:16","guid":{"rendered":"https:\/\/www.herbalreality.com\/?post_type=herb&#038;p=13150"},"modified":"2025-05-23T08:51:09","modified_gmt":"2025-05-23T07:51:09","slug":"aniseed","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/aniseed\/","title":{"rendered":"Aniseed"},"content":{"rendered":"","protected":false},"featured_media":13156,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_project_id":"47224","beyondwords_content_id":"f6463579-d9c5-42e0-8704-5d4afe71b626","beyondwords_preview_token":"943bf2d2-938c-4910-9938-740a931e1b5b","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[1782],"conditions":[685,693,698,695,702],"sustainability":[1576],"sense":[17,27],"western_action":[994,990,992,993,997,999,1003,1008,1010,1012,1018,1021],"chinese_action":[],"ayurvedic_action":[],"energetics_action":[1380,1487,1379,1488,1490,1494],"region":[1897],"class_list":["post-13150","herb","type-herb","status-publish","has-post-thumbnail","hentry","tag-parturient","conditions-digestive-system","conditions-endocrine-system","conditions-reproductive-system","conditions-respiratory-system","conditions-stages-of-life","sustainability-green-sustainability-status","sense-aromatic","sense-sweet","western_action-antioxidant","western_action-analgesic","western_action-anti-inflammatory","western_action-antimicrobial","western_action-antispasmodic","western_action-aphrodisiac","western_action-carminatives","western_action-diuretic","western_action-expectorant","western_action-galactagogue","western_action-relaxant","western_action-stomachic","energetics_action-warm","energetics_action-dry","energetics_action-hot","energetics_action-moist","energetics_action-relaxing","energetics_action-sweet","region-ayurvedic-herbs"],"acf":{"last_reviewed":"20240726","herb_author":1910,"banner_text":"Aniseed supports the digestive and respiratory systems","latin_name":"<em>Pimpinella anisum<\/em>","pseudonym_name":"","family_name":"Apiaceae","herb_summary":"The aromatic oils in aniseed help relieve digestive discomfort and bloating, as well as supporting the respiratory system and women\u2019s health.","key_benefits":"Digestion\r\nRespiratory support\r\nLactation\r\nMenopause","how_does_it_feel":"<span style=\"font-weight: 400;\">An infusion of the seeds (ground slightly before steeping) provides a deep, golden-orange tea, which appear thick and enticing. You can also chew directly on the seeds to release the oils and aromatic sweetness. The infusion smells sweet, fragrant and slightly earthy, reminiscent of fennel and licorice, which is inviting to drink. It is the volatile oils that give this characteristic sweet, aromatic scent and flavour (1). The taste is more bland than expected from the aroma, indicating the presence of volatile oils on the stream. The taste is sweet and comforting, with a slightly sharp sourness, due to the volatile oils. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The sweetness quickly dissipates leaving a more earthy taste in the mouth, with only a mild after-taste, and no astringency or bitterness. There is a heartiness to drinking this tea that is almost nutty and feels nutritious and filling. It can be felt gently moving down through the digestive tract creating a relaxation that can be felt throughout the intestines. This is due to the aromatic oils, exerting spasmolytic and carminative actions throughout the digestive tract.<\/span>","hdif_image_1":13153,"hdif_image_2":13156,"hdif_image_3":13154,"hdif_video":"","sense":[17,27],"what_can_i_use_it_for":"[caption id=\"attachment_13156\" align=\"alignright\" width=\"369\"]<img class=\" wp-image-13156\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum-600x400.jpg\" alt=\"Aniseed yellow (Pimpinella anisum)\" width=\"369\" height=\"246\" \/> Aniseed (<em>Pimpinella anisum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Aniseed is a soothing, aromatic, carminative, similar to fennel, used to settle the stomach and help expel trapped gas (2). It works well to ease intestinal griping, colic, indigestion (dyspepsia), bloating, trapped wind and flatulence (3, 4). The aromatic taste can also help to freshen the breath and improve halitosis (bad breath) (5).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed is antispasmodic and will help a spasmodic cough, bronchial asthma and whooping cough (6). The mucolytic and expectorant actions help to thin mucus and break up catarrh so it can be more easily expelled from the lungs (2, 4). Aniseed is also antimicrobial, so combined with the other actions on the lungs it works well to prevent infections from developing in the lung tissue (3).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed can be taken to increase milk secretion and support lactation (6, 7). <\/span>\r\n\r\n<i><span style=\"font-weight: 400; color: #ed6e17;\">Safety note: See section on safety before taking aniseed during pregnancy or lactation.<\/span><\/i><span style=\"font-weight: 400;\">\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The pleasant-tasting, licorice-like seeds can be added as flavour to foods such as breads, cakes, biscuits, soups and pickles (1). When incorporated into food, the seeds add flavour and act as a digestive aid and breath freshener (5). Many alcoholic drinks which are considered an \u201caperitif\u201d contain anise, such as Pernod, Ouzo and Anisette (5).\u00a0<\/span>","into_the_heart_of":"<span style=\"font-weight: 400;\">Aniseed is sweet and pungent, warm, and dry (2, 5). Wood described aniseed as warm and moist, and suited to tissue states that are atrophic and cold (4). An atrophic tissue state refers to a dryness and lack of fluids or oils in a tissue (4). This impairs the functioning of the body as there is a difficulty absorbing nutrients or removing waste. An indication for an atrophic tissue state would be dry skin, nervousness, restlessness, constipation, gas and bloating (4). Cold and dry tissues require the nourishment, relaxation, movement, warmth and oils, which can all be provided by aniseed. Interestingly, aniseed can be drying where there is excessive mucus in the lungs and digestive tract, yet bring moisture and function back to very dry tissues.<\/span>","tradtional_uses":"[caption id=\"attachment_13155\" align=\"alignright\" width=\"463\"]<img class=\" wp-image-13155\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091713\/Aniseed-seeds-Pimpinella-anisum-600x311.jpg\" alt=\"Aniseed seeds (Pimpinella anisum)\" width=\"463\" height=\"240\" \/> Aniseed seeds (<em>Pimpinella anisum<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Aniseed has been used in England since the 14th century (8). It was used as a spice in cakes, cordials and liqueurs to be consumed at the end of a meal to prevent indigestion (8).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In 1898 King\u2019s American Dispensary listed aniseed as a stimulant carminative, to be used for flatulence, flatulent colic in infants, and nausea (9). It was also recommended as an addition to other medicines to improve flavour and prevent griping and intestinal side effects (9). Aniseed was listed as a carminative in the British Pharmaceutical Codex (BPC) in 1911, recommended to physicians to be added as an ingredient in cathartic formulas to counteract any discomfort and griping caused by purgative herbs (10). Grieve supports the reputation as a carminative for flatulence, colic and griping, recommending an infusion in water or 4\u201320 drops of essential oil on sugar (8). It was also used for hiccups, headaches, and the seeds chewed as a breath freshener (11).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The BPC also <\/span><span style=\"font-weight: 400;\">listed it <\/span><span style=\"font-weight: 400;\">as an ingredient for cough mixtures due to the expectorant action (9). It was used for bronchial catarrh, pertussis (whooping cough), spasmodic cough, persistent cough, tracheitis and bronchitis (12). Grieve reports the value as a medicine for hard, dry coughs, that are difficult to expectorate. For lung conditions it was used in the form of lozenges, as well as the seeds being smoked to promote expectoration (8). A liqueur flavoured with aniseed was given for bronchitis and spasmodic asthma to soothe the bronchial tubes (8). Aniseed is still a commonly used traditional medicine for the treatment of respiratory ailments in Egypt (13).\u00a0\u00a0\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed was traditionally used as an abortifacient (2). This is likely due to the mild oestrogenic action, stimulating the uterus (2). This oestrogenic effect also explains its use in folk medicine to increase libido, facilitate birth, and increase milk secretion during lactation (3). It has a long tradition globally as a galactagogue to support lactation (14, 15).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Additionally, aniseed has reported uses in traditional medicine as an analgesic for migraine headaches, as a diuretic, for melancholy, for nightmares, and to treat epilepsy and seizures (1).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Topically, aniseed was used for pediculosis (head lice) and scabies (12).<\/span>","what_practioners_say":"[caption id=\"attachment_13158\" align=\"alignright\" width=\"600\"]<img class=\"size-medium wp-image-13158\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091729\/Aniseed-flowers-Pimpinella-anisum-600x450.jpg\" alt=\"Aniseed flowers (Pimpinella anisum)\" width=\"600\" height=\"450\" \/> Aniseed flowers (<em>Pimpinella anisum<\/em>)[\/caption]\r\n<h3>Digestive system<\/h3>\r\n<span style=\"font-weight: 400;\">The carminative and antispasmodic actions of aniseed make this herb suited to most dyspeptic conditions including colic, stomach cramps, bloating, belching, nausea and flatulence (4, <\/span><span style=\"font-weight: 400;\">16). Clinical trials have shown that aniseed powder is effective for the treatment of functional dyspepsia (17), and this can significantly improve quality of life of these patients (18). Aniseed can alleviate symptoms of IBS, including abdominal discomfort or pain, bloating, diarrhoea, constipation severity, difficulty in defecation, gastroesophageal reflux, headache, tiredness, and improve QOL <\/span><span style=\"font-weight: 400;\">(19, 20)<\/span><span style=\"font-weight: 400;\">.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">For digestive symptoms of bloating, nausea, uncomfortable trapped wind, flatulence and low appetite, a<\/span><span style=\"font-weight: 400;\">niseed mixes well with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/fennel\/\"><span style=\"font-weight: 400;\">fennel<\/span><\/a><span style=\"font-weight: 400;\"> and caraway seed (3). Aniseed is also effective and safe for colic in young children and babies (4). <\/span><span style=\"font-weight: 400;\">The essential oil components are responsible for the carminative and antispasmodic action, and also the antimicrobial and antioxidant properties which can further support <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/digestive-health\/\"><span style=\"font-weight: 400;\">digestive <\/span><span style=\"font-weight: 400;\">health<\/span><\/a><span style=\"font-weight: 400;\"> (21).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">For the treatment of nausea, aniseed combines well with <\/span><span style=\"font-weight: 400;\">fennel<\/span><span style=\"font-weight: 400;\"> seed, <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/chamomile\/\"><span style=\"font-weight: 400;\">chamomile<\/span><\/a><span style=\"font-weight: 400;\">, and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/mint\/\"><span style=\"font-weight: 400;\">peppermint<\/span><\/a><span style=\"font-weight: 400;\"> (22). Halitosis (bad breath) can stem from digestive weakness, or stagnation in the intestines where tension is inhibiting movement (4). Aniseed can support this by both sweetening the breath, and relaxing tension in the intestines to allow movement to return. For digestive stagnation and bilious nausea, aniseed combines well with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/dandelion\/\"><span style=\"font-weight: 400;\">dandelion<\/span><\/a><span style=\"font-weight: 400;\"> root or <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/artichoke\/\"><span style=\"font-weight: 400;\">artichoke<\/span><\/a><span style=\"font-weight: 400;\"> leaf.\u00a0<\/span>\r\n<h3>Respiratory system<\/h3>\r\n<span style=\"font-weight: 400;\">Aniseed can be used when there is excessive mucus in the lungs causing a wet or boggy cough (3). Aniseed is a warming expectorant which is indicated when the lungs are congested, cold and damp (4). <\/span><span style=\"font-weight: 400;\">Aniseed also directly increases the mucociliary transport of mucus out of the lungs (3). <\/span><span style=\"font-weight: 400;\">When the mucus is stuck and difficult to cough up, the <\/span><span style=\"font-weight: 400;\">mucolytic and expectorant actions help to thin mucus so it can be more easily expelled from the lungs (2). The antispasmodic action also makes aniseed suited to a dry, persistent or spasmodic cough, such as occurs with whooping cough or asthma (11). The antimicrobial properties make aniseed an excellent herb for cases of acute and chronic bronchitis (6). F<\/span><span style=\"font-weight: 400;\">or bronchitis, it combines well with coltsfoot, <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/white-horehound\/\"><span style=\"font-weight: 400;\">white horehound<\/span><\/a><span style=\"font-weight: 400;\"> and lobelia (3).\u00a0<\/span>\r\n<h3>Reproductive system<\/h3>\r\n<span style=\"font-weight: 400;\">Aniseed has a galactagogue action and was used as a traditional medicine to increase milk production and stimulate milk flow (<\/span><span style=\"font-weight: 400;\">25<\/span><span style=\"font-weight: 400;\">). Recently, a large-scale global survey identified aniseed as one of the most commonly used herbs during lactation, along with <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/fennel\/\"><span style=\"font-weight: 400;\">fennel<\/span><\/a><span style=\"font-weight: 400;\">, <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/fenugreek\/\"><span style=\"font-weight: 400;\">fenugreek<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/shatavari\/\"><span style=\"font-weight: 400;\">shatavari<\/span><\/a><span style=\"font-weight: 400;\"> (15). This action and a positive effect on milk production has been demonstrated in animal research (25) and in a human clinical trial (7). One of the primary constituents, a<\/span><span style=\"font-weight: 400;\">nethole, is structurally similar to dopamine and competitively antagonises the dopamine receptor site (7, 25). This removes the inhibitory effect of dopamine on prolactin release, and stimulates milk production<\/span><span style=\"font-weight: 400;\"> (<\/span><span style=\"font-weight: 400;\">25<\/span><span style=\"font-weight: 400;\">). Increased milk secretion can prevent colic in the baby, as well as delivering the aniseed through the breast milk to further support the digestion of the baby (4).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed is an effective herb to reduce the frequency and severity of hot flushes during the menopause transition (26), and premenstrual syndrome (PMS) in menstruating females (<\/span><span style=\"font-weight: 400;\">27<\/span><span style=\"font-weight: 400;\">). When combined with other ingredients such as <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/celery-seeds\/\"><span style=\"font-weight: 400;\">celery seed<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.herbalreality.com\/herb\/saffron\/\"><span style=\"font-weight: 400;\">saffron<\/span><\/a><span style=\"font-weight: 400;\">, aniseed can improve menstrual cramps (dysmenorrhea) and symptoms in cases of polycystic ovary syndrome (PCOS) (24). <\/span><span style=\"font-weight: 400;\">Isolated constituents from the volatile oils in aniseed have demonstrated oestrogenic effects in laboratory assays (28). It is the combined effects on prolactin secretion, the mild o<\/span><span style=\"font-weight: 400;\">estrogenic action and the antispasmodic action which contribute to the mechanism for the increased lactation, improved menstrual dysregulation, and mitigation of menopausal hot flashes (2, 24).<\/span><span style=\"font-weight: 400;\">\u00a0<\/span>\r\n<h3>External uses<\/h3>\r\n<span style=\"font-weight: 400;\">The volatile oils in aniseed have anti-bacterial, insecticidal and antifungal activity (22) and an oil extract can be used to treat pediculosis (head lice) or scabies (3, 12). The essential oil can be added to a carrier oil and applied directly to the skin or scalp. The extracted essential oil is analgesic, and can be used in topical applications where pain mitigation is required (<\/span><span style=\"font-weight: 400;\">22).\u00a0<\/span>","research":"[caption id=\"attachment_13154\" align=\"alignright\" width=\"600\"]<img class=\"size-medium wp-image-13154\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091709\/Aniseed-seed-Pimpinella-anisum-600x400.jpg\" alt=\"Aniseed seed (Pimpinella anisum)\" width=\"600\" height=\"400\" \/> Aniseed seed (<em>Pimpinella anisum<\/em>)[\/caption]\r\n<h3>Digestive system<\/h3>\r\n<span style=\"font-weight: 400;\">Ghoshegir and colleagues (2015) conducted a double blind, randomised clinical trial to assess the effect of aniseed on symptoms of postprandial distress in patients with functional dyspepsia (17). For a duration of four weeks, 107 patients randomly received either aniseed powder after meals (3 g, three times per day) or a placebo. Overall symptoms (including gastric discomfort, bloating, belching, fullness, pain) significantly improved in the aniseed group at weeks 2 and 4, and this improvement was maintained at the 12-week follow up. This was significantly different to the placebo group, where overall symptoms progressively worsened over the 12 weeks (17). The same group of patients reported a significant increase in all components of a quality of life (QOL) scale (including physical functioning, pain, mental health and general health) when taking the aniseed powder (18). Overall QOL significantly decreased in the placebo group, demonstrating the efficacy of aniseed powder in improving QOL in patients with functional dyspepsia (18).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">A double-blind, parallel group clinical trial of 120 patients with irritable bowel syndrome (IBS) compared aniseed oil capsules (600 mg per day) to a commercially available treatment (Colpermin, 187 mg) and a placebo <\/span><span style=\"font-weight: 400;\">(19).<\/span><span style=\"font-weight: 400;\"> The 200 mg capsules were taken three times per day, after each meal, for a duration of four weeks. The improvement in symptoms in the aniseed group was significantly greater than the other conditions, with 75% of patients free from symptoms, and only 52% and 35% for the Colpermin and placebo groups, respectively <\/span><span style=\"font-weight: 400;\">(19).<\/span><span style=\"font-weight: 400;\"> The greatest improvement occurred in the symptoms of reflux, abdominal pain, and bloating, and was maintained at the two-week follow up after the treatment ended. The same group of participants experienced a significant decrease in symptoms of depression when taking the aniseed, compared to the other two conditions <\/span><span style=\"font-weight: 400;\">(23)<\/span><span style=\"font-weight: 400;\">.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">A recent randomised, placebo-controlled trial, published in 2024 investigated the efficacy and safety of aniseed powder for treating gastrointestinal symptoms in patients with COVID-19 (20). In the treatment group, 45 patients took 50 g aniseed powder per day (25 g, twice per day), compared to 180 patients taking a placebo, for two weeks. Compared to the placebo group, the aniseed treatment significantly improved symptoms of abdominal pain, loss of appetite and diarrhoea, but not flatulence or nausea. The authors concluded that aniseed may directly inhibit the viral replication and reduce the COVID-19 pathological process with anti-inflammatory, antioxidant and hepatoprotective actions, reducing any associated gut dysbiosis (20).<\/span>\r\n\r\n[caption id=\"attachment_13153\" align=\"alignleft\" width=\"600\"]<img class=\"size-medium wp-image-13153\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091705\/Aniseed-plant-Pimpinella-anisum-600x450.jpg\" alt=\"Aniseed plant (Pimpinella anisum)\" width=\"600\" height=\"450\" \/> Aniseed plant (<em>Pimpinella anisum<\/em>)[\/caption]\r\n<h3>Female reproductive system<\/h3>\r\n<span style=\"font-weight: 400;\">A study in 2021 reviewed the research exploring the efficacy of aniseed for female disorders, and identified five clinical trials. The study concluded that aniseed is effective in treatment of postpartum pain, menstrual pain (dysmenorrhea), PCOS, hot flash during menopause and improved lactation (24). The majority of the studies used aniseed combined with other ingredients, though aniseed did make up a large proportion (75%) of the formulas.\u00a0<\/span>\r\n<h4>Lactation<\/h4>\r\n<span style=\"font-weight: 400;\">Khalili et al. (2023) conducted a human clinical trial to investigate the effect of aniseed on lactation and weight gain in preterm infants (7). Three parallel groups of participants consumed either aniseed tea (6 g per day), black tea placebo, or no intake control, for seven days. With the exception of day two, the aniseed tea resulted in a significantly greater daily volume of milk production than the placebo or control groups. There was an increase in milk production in all groups from day 1\u20137, but the magnitude of the increase was far greater in the aniseed group compared to the placebo or control (131 ml, 38 ml, and 42 ml, respectively). No adverse side effects were reported in the study, and it was concluded that aniseed is a safe and effective herbal tea to increase lactation, and support weight gain in preterm infants (7).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Using an animal model, both a water and alcohol extract of aniseed (0.5 and 1 g\/kg) significantly increased milk production and infant weight gain in rats (25). The study demonstrated a therapeutic effect at these doses, and also that high doses<\/span><span style=\"font-weight: 400;\"> (3\u20135 g\/kg) had low toxicity, and low risk to suckling infants <\/span><span style=\"font-weight: 400;\">(<\/span><span style=\"font-weight: 400;\">25<\/span><span style=\"font-weight: 400;\">).<\/span>\r\n<h4>PMS<\/h4>\r\n<span style=\"font-weight: 400;\">A randomised double-blind controlled clinical trial of 68 menstruating females with PMS explored the effect of aniseed capsules on symptoms (<\/span><span style=\"font-weight: 400;\">27<\/span><span style=\"font-weight: 400;\">). Either 330 mg of aniseed or a placebo capsule was consumed for two consecutive menstrual cycles. The authors conclude that aniseed was effective at significantly decreasing symptoms of PMS. However, the results should be interpreted with caution, since closer inspection of the data shows there was also a significant decrease in symptoms in the placebo group (<\/span><span style=\"font-weight: 400;\">27<\/span><span style=\"font-weight: 400;\">).\u00a0<\/span>\r\n<h4>Menopause<\/h4>\r\n<span style=\"font-weight: 400;\">A clinical trial of 72 postmenopausal women compared the effect of aniseed capsules (300 mg, three times per day) to a placebo control group (26). The frequency and severity of hot flashes were assessed at baseline and after four weeks. In the aniseed group, the frequency of hot flashes significantly decreased, with no difference in the placebo group. The severity of the hot flashes significantly decreased by 75% in the aniseed group when compared to the placebo group (26).\u00a0<\/span>","did_you_know":"<span style=\"font-weight: 400;\">Aniseed is a key ingredient in liqueurs such as Pernod, Pastis, Ouzo, and Sambuca, which are traditionally consumed after meals as a \u201cdigestif\u201d to support digestion. <\/span>","additional_information_right":{"illustration":13159},"additional_information_left":{"botany":"<span style=\"font-weight: 400;\">Aniseed comes from the anise plant, an annual which grows to about two feet (60 cm) tall (5). The bright green feathery leaves are divided into many leaflets (5, 8). It has clusters of white flowering umbels, which flower in midsummer (5, 8). The small fruit (seeds) appear in the late summer (5). Seeds are grey-green and hairy, drying to a yellow-brown colour (11). <\/span>","common_names":"<ul>\r\n \t<li>Anise<\/li>\r\n \t<li>Anis (German)<\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400;\">Aniseed is safe to consume as medicine and in cooking, although some caution is warranted in cases of allergic sensitivity and during pregnancy and breast-feeding. Aniseed is safe for consumption by children, infants and babies, but the dose needs to be adjusted based on age or body size. Aniseed should not be confused with star anise (<\/span><i><span style=\"font-weight: 400;\">Illicium <\/span><\/i><span style=\"font-weight: 400;\">spp.), which can have toxic effects in children (4).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Regarding breastfeeding, a human clinical trial reported no adverse effects with a dose of 6 g per day for seven days (7). In animal models, even at high doses (2\u20135 g\/kg), aniseed extracts have demonstrated low toxicity, and low risk to a neonate when during breastfeeding <\/span><span style=\"font-weight: 400;\">(<\/span><span style=\"font-weight: 400;\">25<\/span><span style=\"font-weight: 400;\">). However, the transferability of this data to humans requires context and individual evaluation, and aniseed should only be consumed during pregnancy and lactation under the supervision of a qualified medical herbalist. <\/span>","interactions":"<span style=\"font-weight: 400;\">Based on data from human clinical trials there is a possibility of aniseed having a drug interaction with: antidiabetic medications; contraceptive drugs; oestrogens; tamoxifen (29). Always consult with a medical herbalist before taking herbs with possible drug interactions. <\/span>","contraindications":"<span style=\"font-weight: 400;\">Aniseed should be avoided internally and externally by those with allergic hypersensitivity to anise or anethole (30). Aniseed oil may cause contact dermatitis and should be avoided in inflammatory or allergic skin conditions (12).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed has a relaxing effect on the lower oesophageal sphincter and should not be taken by anyone who experiences acid reflux from the stomach into the oesophagus (30).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Due to the potential estrogenic effects of anise it should be avoided in hormone sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, and uterine fibroids (29).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Avoid in pregnancy due to the estrogenic effects of the essential oils (anethole) in aniseed, and the traditional use as an abortifacient (2, 30). Although aniseed is used to promote lactation, and low toxicity is evident from clinical trials, only consume when breast-feeding under the guidance of a medical practitioner (30). You can find qualified medical herbal professionals on our <\/span><a href=\"https:\/\/www.herbalreality.com\/resources\/find-herbalist\/\"><span style=\"font-weight: 400;\">Resource page<\/span><\/a><span style=\"font-weight: 400;\">. <\/span>","preparation":"<strong>Infusion:<\/strong><span style=\"font-weight: 400;\"> The seeds should be gently crushed just before use to release the volatile oils contained in the external coat of the seed (3, 9). Leave to steep for 5\u201310 minutes in a covered cup\/pot to prevent the volatile oils from escaping (3).<\/span> <span style=\"font-weight: 400;\">Drink before meals to treat flatulence, and after meals to support digestion (3).\u00a0<\/span><b>\u00a0<\/b>","dosage":"<strong>Infusion<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> \u00bd\u20131 teaspoon (0.5\u20131 g), 1\u20133 times per day (3, 11). Take 50\u2013200ml, three times a day (2).\u00a0\u00a0<\/span>\r\n\r\n<strong>Tincture (1,5, <\/strong><span style=\"font-weight: 400;\"><strong>40\u201350%):<\/strong> 1\u20133 ml, 3 times per day (2, 3). Up to 20\u201340 ml\/week of a 1:2 extract (6)<\/span>\r\n\r\n<strong>Topical<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> Preparations containing 5\u201310% essential oil (<\/span><span style=\"font-weight: 400;\">16<\/span><span style=\"font-weight: 400;\">)<\/span>\r\n\r\n<strong>Powder<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> 1\u20139 g per day (17, 18, 26). Up to 20 g per day (12)<\/span>\r\n\r\n<strong>Aniseed oil capsules<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> 600 mg per day (19)<\/span>\r\n\r\n<strong>Aniseed extract capsules<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> 900 mg per day (26)<\/span>","constituents":"<ul>\r\n \t<li><strong>Essential oils (1.5\u20136%)<\/strong><span style=\"font-weight: 400;\"><strong>:<\/strong> Anethol (70\u201395%), dianethole, photoanethole, estragole (3, 6, 8, 12)<\/span><\/li>\r\n \t<li><strong>Fatty oils (8\u201330%)<\/strong> (3, 6, 11)<\/li>\r\n \t<li><strong>Coumarins<\/strong><strong>:<\/strong> Bergapten, umbelliferone, scopoletin (3, 12).<\/li>\r\n \t<li><strong>Flavonoids<\/strong><strong>:<\/strong> Rutin, isovitexin, quercetin, luteolin, apigenin (3, 12)<\/li>\r\n \t<li><strong>Phenylpropenyl esters (oil soluble)<\/strong><strong>:<\/strong> Anethole (6, 21)<\/li>\r\n<\/ul>","plant_part_used":"<span style=\"font-weight: 400;\">Dried seeds \/ fruit<\/span>"},"habitat":"<span style=\"font-weight: 400;\">Aniseed is native to Turkey, Israel, Lebanon, Syria, Cyprus, and Egypt (31). It has been introduced across southern and eastern Europe, India, North Africa, Central and South America, and China (31).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It is an annual and grows primarily in countries with a warm temperature biome (31). It is cultivated in English gardens but the seeds only ripen during hot summers (8).<\/span>","sustainability":"<img class=\" wp-image-10530 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2023\/10\/09115149\/sustainability-icon-green.jpg\" alt=\"\" width=\"268\" height=\"268\" \/>\r\n\r\n<span style=\"font-weight: 400;\">Habitat loss and over-harvesting from the wild are two of the biggest threats faced by medicinal plant species. There are an increasing number of well-known herbal medicines at risk of extinction. We must, therefore, ensure that we source our medicines with sustainability in mind.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The herb supplement industry is growing at a rapid rate and until recent years a vast majority of medicinal plant produce in global trade was of unknown origin. There are some very real and urgent issues surrounding sustainability in the herb industry. These include environmental factors that affect the medicinal viability of herbs, the safety of the habitats that they are taken from, as well as the welfare of workers in the trade.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The botanical supply chain efforts for improved visibility (transparency and traceability) into verifiably sustainable production sites around the world are now certificated through the emergence of credible international voluntary sustainability standards (VSS).<\/span><span style=\"font-weight: 400;\">\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality and safety: What to know before you buy<\/span><\/a>\u00a0<span style=\"font-weight: 400;\">and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed is not listed on CITES (32), is unranked by Nature serve (33), and is not listed by United Plant Savers (34) nor IUCN (35).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Aniseed has no status ranking by Nature Serve, it does not appear on the U.S. Endangered Species Act (33), it is not listed by the International Union for Conservation of Nature (IUCN) (35), and it is not on the United Plant Savers \u201cSpecies at-risk\u201d list (34). <\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"<span style=\"font-weight: 400;\">Herbal medicines are often very safe to take, however, it is important to buy herbal medicines from a reputed supplier. Sometimes herbs bought from disreputable sources are contaminated, adulterated or substituted with incorrect plant matter.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Some important markers for quality to look for would be to look for certified organic labelling, ensuring that the correct scientific\/botanical name is used and that suppliers can provide information about the source of ingredients used in the product.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">A supplier should be able to tell you where the herbs have come from. There is more space for contamination and adulteration when the supply chain is unknown.<\/span>","how_to_grow":"<span style=\"font-weight: 400;\">The plant only grows from seed, sown in spring, and will only mature to seed if the weather is warm enough (8, 11). It prefers dry, light soil in full sun (5). The seeds (fruit) are gathered from July\u2013September, when ripe and dry (3, 11). <\/span>","recipe":"<span style=\"font-weight: 400;\">Aniseeds can be added to cakes, puddings, breads and biscuits.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Take a look at this delicious recipe for <\/span><a href=\"https:\/\/freshaprilflours.com\/italian-anise-bread\/\"><span style=\"font-weight: 400;\">Italian Aniseed Bread<\/span><\/a><span style=\"font-weight: 400;\">.<\/span>","references":"<ol>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sun W, Shahrajabian MH, Cheng Q. Anise (Pimpinella anisum L.), a dominant spice and traditional medicinal herb for both food and medicinal purposes. <\/span><i><span style=\"font-weight: 400;\">Cogent Biology<\/span><\/i><span style=\"font-weight: 400;\">. 2019;5(1):1673688. <\/span><a href=\"https:\/\/doi.org\/10.1080\/23312025.2019.1673688\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1080\/23312025.2019.1673688<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Easley T, Horne S. <\/span><i><span style=\"font-weight: 400;\">The Modern Herbal Dispensatory: A Medicine-Making Guide<\/span><\/i><span style=\"font-weight: 400;\">. North Atlantic Books; 2016.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hoffmann D.\u00a0<\/span><i><span style=\"font-weight: 400;\">Medicinal Herbalism, The Science and Practice of Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Healing Arts Press; 2003.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Wood M.\u00a0<\/span><i><span style=\"font-weight: 400;\">The Earthwise Herbal Volume 1: A Complete Guide to Old World Medicinal Plants<\/span><\/i><span style=\"font-weight: 400;\">. North Atlantic Books; 2008.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mars, B. <\/span><i><span style=\"font-weight: 400;\">The Desktop Guide to Herbal Medicine.<\/span><\/i><span style=\"font-weight: 400;\"> Basic Health Publications Inc; 2007.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bone K and Mills S.\u00a0<\/span><i><span style=\"font-weight: 400;\">Principles and Practice of Phytotherapy: Modern Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Elsevier Health Sciences; 2013.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Khalili S, Amiri-Farahani L, Haghani S, Bordbar A, Shojaii A, Pezaro S. The effect of Pimpinella Anisum herbal tea on human milk volume and weight gain in the preterm infant: a randomized controlled clinical trial. <\/span><i><span style=\"font-weight: 400;\">BMC complementary medicine and therapies<\/span><\/i><span style=\"font-weight: 400;\">. 2023;23(1):19. <\/span><a href=\"https:\/\/doi.org\/10.1186\/s12906-023-03848-6\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1186\/s12906-023-03848-6<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grieve M, Leyel CF, Marshall M. <\/span><i><span style=\"font-weight: 400;\">A Modern Herbal. the Medicinal, Culinary, Cosmetic and Economic Properties, Cultivation and Folk-Lore of Herbs, Grasses, Fungi, Shrubs &amp; Trees with All Their Modern Scientific Uses<\/span><\/i><span style=\"font-weight: 400;\">. Dover Publications; 1982.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Felter H. W, Lloyd J. U (1898) King\u2019s American Dispensary 18th Edit. Reprinted on Henritttas Herbpages. Accessed June 26, 2024. <\/span><a href=\"https:\/\/www.henriettes-herb.com\/eclectic\/kings\/pimpinella-anis.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.henriettes-herb.com\/eclectic\/kings\/pimpinella-anis.html<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">British Pharmaceutical Codex (1911). Anise Fruit. Reprinted on Henrietta\u2019s Herbpages. Accessed June 26, 2024. <\/span><a href=\"https:\/\/www.henriettes-herb.com\/eclectic\/bpc1911\/pimpinella.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.henriettes-herb.com\/eclectic\/bpc1911\/pimpinella.html<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fisher C. <\/span><i><span style=\"font-weight: 400;\">Materia Medica of Western Herbs<\/span><\/i><span style=\"font-weight: 400;\">. Aeon Books; 2018.\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Barnes, J., Anderson, L.A. and Phillipson, J.D. <\/span><i><span style=\"font-weight: 400;\">Herbal medicines: a guide for healthcare professionals:<\/span><\/i><span style=\"font-weight: 400;\"> Third Edition. Pharmaceutical press; 2007.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">AbouZid SF, Mohamed AA. Survey on medicinal plants and spices used in Beni-Sueif, Upper Egypt. <\/span><i><span style=\"font-weight: 400;\">J Ethnobiol Ethnomed.<\/span><\/i><span style=\"font-weight: 400;\"> 2011;7:18. doi:10.1186\/1746-4269-7-18<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Javan R, Javadi B, Feyzabadi Z. Breastfeeding: A review of its physiology and galactagogue plants in view of traditional Persian medicine. <\/span><i><span style=\"font-weight: 400;\">Breastfeeding Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2017;12(7):401-9. <\/span><a href=\"https:\/\/doi.org\/10.1089\/bfm.2017.0038\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1089\/bfm.2017.0038<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Sibeko L, Johns T. Global survey of medicinal plants during lactation and postpartum recovery: Evolutionary perspectives and contemporary health implications. <\/span><i><span style=\"font-weight: 400;\">Journal of Ethnopharmacology<\/span><\/i><span style=\"font-weight: 400;\">. 2021;270:113812. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.jep.2021.113812\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.jep.2021.113812<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Blumenthal M, Busse WR. Anise Seed. In: <\/span><i><span style=\"font-weight: 400;\">The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines<\/span><\/i><span style=\"font-weight: 400;\">. American Botanical Council; 1999. Accessed June 26, 2024. <\/span><a href=\"https:\/\/www.herbalgram.org\/resources\/commission-e-monographs\/monograph-approved-herbs\/anise-seed\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.herbalgram.org\/resources\/commission-e-monographs\/monograph-approved-herbs\/anise-seed\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ghoshegir SA, Mazaheri M, Ghannadi A, Feizi A, Babaeian M, Tanhaee M, Karimi M, Adibi P. Pimpinella anisum in the treatment of functional dyspepsia: A double-blind, randomized clinical trial. <\/span><i><span style=\"font-weight: 400;\">Journal of Research in Medical Sciences<\/span><\/i><span style=\"font-weight: 400;\">. 2015;20(1):13-21. <\/span><a href=\"https:\/\/journals.lww.com\/jrms\/fulltext\/2015\/20010\/pimpinella_anisum_in_the_treatment_of_functional.3.aspx\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/journals.lww.com\/jrms\/fulltext\/2015\/20010\/pimpinella_anisum_in_the_treatment_of_functional.3.aspx<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ghoshegir SA, Mazaheri M, Ghannadi A, Feizi A, Babaeian M, Tanhaee M, Karimi M, Adibi P. Pimpinella anisum in modifying the quality of life in patients with functional dyspepsia: A double-blind randomized clinical trial. <\/span><i><span style=\"font-weight: 400;\">Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences. <\/span><\/i><span style=\"font-weight: 400;\">2014 Dec;19(12):1118. <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4333517\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4333517\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mosaffa-Jahromi M, Lankarani KB, Pasalar M, Afsharypuor S, Tamaddon AM. Efficacy and safety of enteric coated capsules of anise oil to treat irritable bowel syndrome. <\/span><i><span style=\"font-weight: 400;\">Journal of ethnopharmacology<\/span><\/i><span style=\"font-weight: 400;\">. 2016;194:937-46. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.jep.2016.10.083\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.jep.2016.10.083<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mosaffa-Jahromi M, Molavi Vardanjani H, Fuzimoto A, Hunter J, Lankarani KB, Pasalar M. Efficacy and safety of aniseed powder for treating gastrointestinal symptoms of COVID-19: a randomized, placebo-controlled trial. <\/span><i><span style=\"font-weight: 400;\">Frontiers in Pharmacology<\/span><\/i><span style=\"font-weight: 400;\">. 2024;15:1331177. <\/span><a href=\"https:\/\/doi.org\/10.3389\/fphar.2024.1331177\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.3389\/fphar.2024.1331177<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ganora, L. Herbal Constituents: <\/span><i><span style=\"font-weight: 400;\">Foundations of Phytochemistry<\/span><\/i><span style=\"font-weight: 400;\">. Herbalchem Press; 2009.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Shojaii A, Abdollahi Fard M. Review of pharmacological properties and chemical constituents of <\/span><i><span style=\"font-weight: 400;\">Pimpinella anisum<\/span><\/i><span style=\"font-weight: 400;\">. <\/span><i><span style=\"font-weight: 400;\">International scholarly research notices<\/span><\/i><span style=\"font-weight: 400;\">. 2012;2012(1):510795. <\/span><a href=\"https:\/\/doi.org\/10.5402\/2012\/510795\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.5402\/2012\/510795<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mosaffa-Jahromi, M., Tamaddon, A. M., Afsharypuor, S., Salehi, A., Seradj, S. H., Pasalar, M., Jafari, P., &amp; Lankarani, K. B. (2017). Effectiveness of Anise Oil for Treatment of Mild to Moderate Depression in Patients With Irritable Bowel Syndrome: A Randomized Active and Placebo-Controlled Clinical Trial.\u00a0<\/span><i><span style=\"font-weight: 400;\">Journal of evidence-based complementary &amp; alternative medicine<\/span><\/i><span style=\"font-weight: 400;\">,\u00a0<\/span><i><span style=\"font-weight: 400;\">22<\/span><\/i><span style=\"font-weight: 400;\">(1), 41\u201346. <\/span><a href=\"https:\/\/doi.org\/10.1177\/2156587216628374\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1177\/2156587216628374<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mahboubi M, Mahboubi M. <\/span><i><span style=\"font-weight: 400;\">Pimpinella anisum<\/span><\/i><span style=\"font-weight: 400;\"> and female disorders: A review. <\/span><i><span style=\"font-weight: 400;\">Phytomedicine Plus<\/span><\/i><span style=\"font-weight: 400;\">. 2021;1(3):100063. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.phyplu.2021.100063\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.phyplu.2021.100063<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hosseinzadeh H, Tafaghodi M, Abedzadeh S, Taghiabadi E. Effect of aqueous and ethanolic extracts of Pimpinella anisum L. seeds on milk production in rats.\u00a0<\/span><i><span style=\"font-weight: 400;\">Journal of Acupuncture and Meridian Studies<\/span><\/i><span style=\"font-weight: 400;\">. 2014;7(4):211-216. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.jams.2013.10.004\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.jams.2013.10.004<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Nahidi F, Taherpour M, Mojab F. Effects of Anise extract on menopausal hot flashes. <\/span><i><span style=\"font-weight: 400;\">Pajoohandeh Journal<\/span><\/i><span style=\"font-weight: 400;\">. 2008;13(3):167-73. <\/span><a href=\"http:\/\/pajoohande.sbmu.ac.ir\/article-1-631-en.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">http:\/\/pajoohande.sbmu.ac.ir\/article-1-631-en.html<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Farahmand M, Khalili D, Tehrani FR, Amin G, Negarandeh R. Could Anise decrease the intensity of premenstrual syndrome symptoms in comparison to placebo? A double-blind randomized clinical trial. <\/span><i><span style=\"font-weight: 400;\">Journal of Complementary and Integrative Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2020;17(4). <\/span><a href=\"https:\/\/doi.org\/10.1515\/jcim-2019-0077\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1515\/jcim-2019-0077<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tabanca N, Khan SI, Bedir E, Annavarapu S, Willett K, Khan IA, Kirimer N, Baser KH. Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. <\/span><i><span style=\"font-weight: 400;\">Planta medica<\/span><\/i><span style=\"font-weight: 400;\">. 2004;70(08):728-35. DOI: 10.1055\/s-2004-827203<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Natural Medicines Professional Database. Therapeutic Research Centre. <\/span><i><span style=\"font-weight: 400;\">Anise Professional Monograph. <\/span><\/i><span style=\"font-weight: 400;\">Published Nov 16, 2023. Accessed June 29, 2024. <\/span><a href=\"https:\/\/naturalmedicines.therapeuticresearch.com\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/naturalmedicines.therapeuticresearch.com\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Brinker, FJ.\u00a0<\/span><i><span style=\"font-weight: 400;\">Herbal Contraindications &amp; Drug Interactions: Plus Herbal Adjuncts with Medicines<\/span><\/i><span style=\"font-weight: 400;\">. Eclectic Medical Publications, 2010.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Royal Botanical Gardens Kew (RBGK).<\/span> <i><span style=\"font-weight: 400;\">Pimpinella anisum<\/span><\/i><span style=\"font-weight: 400;\">\u00a0L. Plants of the Word Online (POWO). Accessed June 19, 2024. <\/span><a href=\"https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:846658-1\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/powo.science.kew.org\/taxon\/urn:lsid:ipni.org:names:846658-1<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). Accessed June 26, 2024. https:\/\/checklist.cites.org\/#\/en\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NatureServe explorer 2.0. Natureserve.org. 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Accessed June 26, 2024. <\/span><a href=\"https:\/\/www.iucnredlist.org\/search\/list?query=Pimpinella_anisum&amp;searchType=species\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.iucnredlist.org\/search\/list?query=Pimpinella_anisum&amp;searchType=species<\/span><\/a><\/li>\r\n<\/ol>","related_condition":[3375,198],"related_herb":[1920,1840],"related_article":[6308,10564],"herb_overview_content_one":"","herb_overview_content_two":"","herb_overview_content_three":"","herb_overview_content_four":"","herb_overview_content_five":"","herb_overview_content_six":"","herb_overview_content_seven":"","herb_overview_content_eight":"","botany":"","botanical_description":"","botanical_image":null,"common_names":"","herbal_preperation_image":null,"preparation":"","plant_part_used":"","dosage":"","constituents":"","recipe_image":null,"safety_post":null,"safety":"","interactions":"","contraindications":"","sustainability_image_one":null,"sustainability_image_two":null,"faqs":null,"not_suitable_for":[]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",1000,667,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum-600x400.jpg",600,400,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",580,387,false],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",1000,667,false],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/07\/26091720\/Aniseed-yellow-Pimpinella-anisum.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 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