{"id":13270,"date":"2024-08-04T10:44:51","date_gmt":"2024-08-04T09:44:51","guid":{"rendered":"https:\/\/www.herbalreality.com\/?post_type=herb&#038;p=13270"},"modified":"2025-06-16T17:07:39","modified_gmt":"2025-06-16T16:07:39","slug":"lesser-periwinkle","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/lesser-periwinkle\/","title":{"rendered":"Lesser periwinkle"},"content":{"rendered":"","protected":false},"featured_media":13275,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_project_id":"47224","beyondwords_content_id":"1e755df6-9656-47bd-971d-e2b896c036d9","beyondwords_preview_token":"36095812-cb56-472f-b062-35b7399b6705","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[1767,1635,1784],"conditions":[694,696],"sustainability":[1576],"sense":[31,18,786],"western_action":[989,1000,1017,1024],"chinese_action":[1168,1050,1044,1047],"ayurvedic_action":[1057,1103],"energetics_action":[1492,1499,1515,1512,1498,1557,1622,1506,1382,1533,1487,1546,1520,1553,1543,1572,1619,1560,1552,1556,1539,1549],"region":[1893],"class_list":["post-13270","herb","type-herb","status-publish","has-post-thumbnail","hentry","tag-antidepressant","tag-hypotensive","tag-ophthalmic","conditions-cardiovascular-system","conditions-nervous-system","sustainability-green-sustainability-status","sense-astringent-taste","sense-bitter","sense-cooling","western_action-alterative","western_action-astringent","western_action-nervine","western_action-vasodilator","chinese_action-clear-heat-dry-damp","chinese_action-astringents-stabilise-bind","chinese_action-stop-bleeding","chinese_action-tonify-blood","ayurvedic_action-rakta-shodhana-rakta-prasadana","ayurvedic_action-stambhana","energetics_action-toning","energetics_action-astringent","energetics_action-astringent-taste-chinese","energetics_action-bitter-taste-chinese","energetics_action-bitter","energetics_action-blood","energetics_action-circulatory","energetics_action-cool-temperature-chinese","energetics_action-cool","energetics_action-cooling","energetics_action-dry","energetics_action-dry-quality","energetics_action-heart","energetics_action-kapha","energetics_action-light","energetics_action-mental","energetics_action-nervous-channel-srotas","energetics_action-nervous","energetics_action-pitta-constitution-dosha","energetics_action-plasma","energetics_action-pungent-post-digestive-effect-vipaka","energetics_action-vata","region-western-herbs"],"acf":{"last_reviewed":"20240804","herb_author":null,"banner_text":"Lesser periwinkle is helpful for neurodegenerative conditions","latin_name":"<em>Vinca minor<\/em>","pseudonym_name":"","family_name":"Apocynaceae","herb_summary":"Pharmaceuticals have been synthesised from the chemicals found naturally in this plant, for conditions of the nervous system. However, there are many more medicinal benefits that periwinkle can provide in the context of traditional herbalism.  ","key_benefits":"Loss of mental focus \/ memory\r\nDizziness \/ headaches\r\nTinnitus\r\nAnxiety, stress and Nervous tension\r\nSeasonal affective disorder\r\nRestorative for anaemia and anorexia\r\nPeripheral arterial deficiency\r\nCerebral arteriosclerosis\r\nPost-stroke","how_does_it_feel":"<span style=\"font-weight: 400;\">Its astringent qualities are due to the tannins it contains, which make periwinkle a useful remedy for drying excessive secretions and tightening and toning tissues.<\/span>","hdif_image_1":13275,"hdif_image_2":13280,"hdif_image_3":13278,"hdif_video":"https:\/\/youtu.be\/kL8VuVLnuVk","sense":[31,18,786],"what_can_i_use_it_for":"<span style=\"font-weight: 400;\">Loss of mental focus, memory, dizziness, headache, tinnitus, vertigo, anxiety, stress, seasonal affective disorder, nervous tension, hypertension, restorative for anaemia and anorexia, peripheral arterial deficiency (as it tones and strengthens blood vessels), and cerebral arteriosclerosis. Therefore, it is also helpful for post-stroke victims. <\/span>","into_the_heart_of":"<span style=\"font-weight: 400;\">It is an energetically cooling plant useful to treat heating conditions and inflammation.<\/span> <span style=\"font-weight: 400;\">It is the indole alkaloids present in lesser periwinkle<\/span> <span style=\"font-weight: 400;\">that are of most interest. It is cited as a cerebral tonic by Matthew Wood (1), and with its vasodilatory and stimulating effects it improves blood flow to the brain and is recommended in cerebral atherosclerosis (plaquing of the arteries) and also said to reduce high blood pressure (2).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">With an increasing prevalence of Alzheimer\u2019s, the ability of <\/span><i><span style=\"font-weight: 400;\">V. minor<\/span><\/i><span style=\"font-weight: 400;\"> to promote cerebral circulation in addition to its potential to ameliorate atherosclerosis makes the herb a good candidate for use for current neurodegenerative challenges.<\/span>","tradtional_uses":"[caption id=\"attachment_13276\" align=\"alignright\" width=\"442\"]<img class=\" wp-image-13276\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104140\/Lesser-periwinkle-blooming-Vinca-minor-600x430.jpg\" alt=\"Lesser periwinkle blooming (Vinca minor)\" width=\"442\" height=\"317\" \/> Lesser periwinkle blooming (<em>Vinca minor<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Periwinkle was understood for its astringent nature in as early as 40\u201390 AD by the Greek physician Dioscorides who noted in his De Materia Medica that <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\"><em>the leaves be drunk in wine to lessen excessive discharges of the bowels......and cure the pain of the matrix (womb)<\/em>\u201d (3).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Pliny (23\u201379 AD) recommended periwinkle for bleeding, diarrhoea, to heal wounds, and as an antidote to poisonous bites when taken with wine. It was even believed to prevent miscarriage when fastened around the thigh of a pregnant woman (McIntyre, 2022) (3).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Apuleius, 5th century, wrote in his herbarium: <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\"><em>This wort is of good advantage....against devil sickness and demoniacal possessions...against snakes and wilde beasts and against poisons....and for envy and terror....that thou may have grace. If thou hast the wort with thee.....prosperous and ever acceptable.<\/em>\u201d (4).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In the 13th century, Boke of Secrets it was said <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\"><em>Perwynke induceth love between man and wife if...used in their meales,<\/em>\u201d (4).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Herbalist John Gerard famously said of its virtues that if <\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\"><em>the leaves stamped, and the juice given to drink in red wine, stoppeth the...... spitting of blood and it likewise stoppeth the inordinate course of the monthly sickness (heavy menses)<\/em>.\u201d\u00a0<\/span>\u00a0(5)\r\n\r\n<span style=\"font-weight: 400;\">One of the most famous herbalists, Nicholas Culpeper, said it could be used it as an aphrodisiac when shared amongst lovers, and that it stopped the bleeding of the mouth and nose and was also good for the nightmares (4,6).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Periwinkle tea was thought of as a good remedy for scurvy, to relax sore throats and inflamed tonsils and to gargle with (4).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Bruised leaves inserted into nostrils were used to stop bleeding, and when used as an ointment with lard for its healing and anti-inflammatory properties, periwinkle was a useful remedy for skin complaints and for bleeding piles. The flowers of <\/span><i><span style=\"font-weight: 400;\">Vinca minor<\/span><\/i><span style=\"font-weight: 400;\"> are thought of as gently purgative when made into a syrup, and considered a gentle laxative for children (4).<\/span>","what_practioners_say":"[caption id=\"attachment_13278\" align=\"alignright\" width=\"429\"]<img class=\" wp-image-13278\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104145\/Lesser-periwinkle-flowers-Vinca-minor-600x399.jpg\" alt=\"Lesser periwinkle flowers (Vinca minor)\" width=\"429\" height=\"285\" \/> Lesser periwinkle flowers (<em>Vinca minor<\/em>)[\/caption]\r\n\r\n<i><span style=\"font-weight: 400;\">V. minor<\/span><\/i><span style=\"font-weight: 400;\"> has a particular affinity to the head and is viewed as a relaxing circulatory stimulant, which helps to clear restriction and promote the free flow of materials. Consequently, oxygen uptake is enhanced and cerebral performance is improved.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Useful in head issues like headaches, indicated for eye disease, ear problems like tinnitus, vertigo and labrynthitis and thought of as helpful in lowering high blood pressure and useful in Alzheimer\u2019s. A synthetic version of an alkaloid from vinca called vinpocetine has been shown in studies to be usefeul for treatment for cognitive impairment and neurodegeneration (22).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Some herbalists<\/span><span style=\"font-weight: 400;\"> substitute for Gin<\/span><span style=\"font-weight: 400;\">g<\/span><span style=\"font-weight: 400;\">ko and think of it as a peripheral vasodilator that improves oxygen and nutrient flow to the brain<\/span><span style=\"font-weight: 400;\">. Therefore it could be used <\/span><span style=\"font-weight: 400;\">for post-stroke victims to enhance the blood flow to that area.<\/span><span style=\"font-weight: 400;\"> However, interestingly many modern clinical herbalists do not use vinca any more despite there being plenty of recorded use in earlier literature.<\/span>","research":"[caption id=\"attachment_13280\" align=\"alignright\" width=\"600\"]<img class=\"size-medium wp-image-13280\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104148\/Lesser-periwinkle-in-a-wood-Vinca-minor-600x399.jpg\" alt=\"Lesser periwinkle in a wood (Vinca minor)\" width=\"600\" height=\"399\" \/> Lesser periwinkle in a wood (<em>Vinca minor<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Almost no<\/span><span style=\"font-weight: 400;\"> studies have been done on whole plant extracts of <\/span><i><span style=\"font-weight: 400;\">Vinca minor<\/span><\/i><span style=\"font-weight: 400;\">, whereas numerous studies have been done using the isolated compound, the indole alkaloid, vincamine.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Vincamine, a vinca alkaloid found in the leaves of <\/span><i><span style=\"font-weight: 400;\">Vinca<\/span><\/i> <i><span style=\"font-weight: 400;\">minor<\/span><\/i><span style=\"font-weight: 400;\"> is the strongest represented constituent and represents about 20\u201325% of all of the 40 or so alkaloids found so far. Specifically, vincamine is a monoterpene indole alkaloid with vasodilatory properties and studies indicate that it increases the regional cerebral blood flow. It is listed here as an antihypertensive, antineoplastic and peripheral vasodilator and vasodilator (5).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Vincamine has peripheral circulatory benefits and is used as a cerebral stimulant and vasodilator due to its ability to pass through the blood brain barrier and modulate brain circulation and neuronal homeostasis (6,7).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The monoterpene indole alkaloids from <\/span><i><span style=\"font-weight: 400;\">Vinca minor<\/span><\/i><span style=\"font-weight: 400;\"> have identified a new structural scaffold for treatment of Alzheimer's disease. There were a number of indole alkaloids that showed both the ability of blood-brain barrier penetration and remarkable hBuChE, and POP inhibition potency (both suggested markers in Alzheimers disease progression) (8).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In a study on the therapeutic efficacy of vincamine in dementia, Fischhof et al. showed in a double-blind placebo-controlled trial of 142 patients between the ages of 50\u201385 years who had either degenerative dementia of the Alzheimer\u2019s type or multi-infarct dementia. After a 12-week time period the controlled group who were given 30mg vincamine twice daily performed significantly better in all four target variables compared to the placebo group (9).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">There was a study done recently by Hasa that showed a sevenfold improvement in oral bioavailability of vincamine when administered to rats as part of a whole plant compared to the pure chemical compound (2013) (10), something we know as the \u2018entourage effect\u2019, which is a major premise of herbalism as we use phytochemically diverse extracts.\u00a0<\/span>","did_you_know":"[caption id=\"attachment_13274\" align=\"alignright\" width=\"353\"]<img class=\" wp-image-13274\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104135\/Lesser-periwinkle-plants-Vinca-minor-600x400.jpg\" alt=\"Lesser periwinkle plants (Vinca minor)\" width=\"353\" height=\"235\" \/> Lesser periwinkle plants (<em>Vinca minor<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">There are actually two very similar plants with different uses: lesser periwinkle and greater periwinkle<\/span><i><span style=\"font-weight: 400;\">. <\/span><\/i><span style=\"font-weight: 400;\">Unlike lesser periwinkle, described above, greater periwinkle (larger leaves) is now known to have an affinity for the reproductive and lower digestive systems, due to its strong astringency and blood staunching actions. It is especially useful to stem heavy menstrual bleeding or to reduce bleeding ulcers in the digestive system.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Lesser periwinkle<\/span> <span style=\"font-weight: 400;\">was known as The Sorcerer<\/span><span style=\"font-weight: 400;\">\u2019<\/span><span style=\"font-weight: 400;\">s Violet or Devils Eye, and it was considered a favourite flower of the<\/span><span style=\"font-weight: 400;\">\u201c<\/span><span style=\"font-weight: 400;\">wise folk (witches) for making charms and love potions. It was even said to be able to exorcise evil spirits (11). It was also said that even staring into the beautiful flower alone could bring back memories.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Periwinkle was considered the Female Patron Herb of Wiccans she was guided by the planet Venus (13).<\/span>","additional_information_right":{"illustration":108882},"additional_information_left":{"botany":"<span style=\"font-weight: 400\">It is an evergreen ground hugging shrub with rooting stems, shiny elliptical leaves and five-petalled elliptical blue-violet flowers (20).<\/span>","common_names":"<ul>\r\n \t<li><span style=\"font-weight: 400\">Blue periwinkle<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400\">Small leaf periwinkle<\/span><\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400\">Alkaloids can have profound physiological actions in humans, especially on the nervous system \u2014e.g. caffeine, morphine, lobeline, berberine, ephedrine (14). So, caution is always prescribed with alkaloids due to their potential strength and toxicity. Therefore, it is suggested that you use caution as high doses may adversely affect the nervous system and kidneys. Always avoid use when pregnant, breastfeeding or with hypotension (15).<\/span>","interactions":"<span style=\"font-weight: 400\">High doses may decrease absorption of digoxin. Due to the hypotensive activity of the constituent vincamine, periwinkle may have an additive effect with antihypertensive drugs, so blood pressure should be closely monitored if using concomitantly.<\/span><span style=\"font-weight: 400\"> Theoretically, due to the antihypertensive activity of the constituent vincamine,<\/span> <span style=\"font-weight: 400\">taking periwinkle may increase the effects of antihypertensive drugs (16).<\/span>","contraindications":"<i><span style=\"font-weight: 400\">Vinca minor <\/span><\/i><span style=\"font-weight: 400\">is contraindicated in brain tumours (17) as it may cause intracranial bleeding and pressure (2,17).<\/span>\r\n\r\n<span style=\"font-weight: 400\">Due to the astringency of V. minor, it is contraindicated in constipation. As it also can lower blood pressure, its use should be avoided in individuals with low blood press and prior to surgery (as it may interfere with blood pressure control) (18).<\/span>","preparation":"<span style=\"font-weight: 400\">In the modern herbalist pharmacy, <\/span><i><span style=\"font-weight: 400\">Vinca minor <\/span><\/i><span style=\"font-weight: 400\">is mainly used as an alcoholic tincture. You can also use in a lotion for haemorrhoids. Due to its astringency, you can chew the leaves of <\/span><i><span style=\"font-weight: 400\">Vinca minor <\/span><\/i><span style=\"font-weight: 400\">and <\/span><i><span style=\"font-weight: 400\">V. major<\/span><\/i><span style=\"font-weight: 400\"> in the case of toothache and bleeding gums (15). Historically, the leaves were steeped in wine and then drunk to staunch bleeding menses, heal wounds and reduce diarrhoea.<\/span>","dosage":"<span style=\"font-weight: 400\"><strong>Alcoholic tincture:<\/strong> Don\u2019t use as a simple (just the one herb), always use as part of a tincture formulae up to a maximum of 25% in any formulae due to potential toxicity.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400\">Then take 5ml three times daily. <\/span><i><span style=\"font-weight: 400\">Vinca minor<\/span><\/i><span style=\"font-weight: 400\"> alcoholic tincture is usually a 1:4 25%.<\/span>","constituents":"<ul>\r\n \t<li><span style=\"font-weight: 400\">Tannins<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400\">Cardiac glycosides<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400\">Contains around 40 indole alkaloids, including vincine, isomajdine, majdine, reseroinine, serpentine, of which vincamine is thought of as the most active<\/span><\/li>\r\n<\/ul>","plant_part_used":"<span style=\"font-weight: 400\">In herbal medicine, you can use the roots, leaves and flowers of <\/span><i><span style=\"font-weight: 400\">Vinca minor. <\/span><\/i><span style=\"font-weight: 400\">The flowers are a gentle laxative when fresh and the roots are antispasmodic and used to lower blood pressure (19).<\/span>"},"habitat":"<span style=\"font-weight: 400;\">Thought to be endemic to Spain initially it then over time found its way to our more northernly shores. Its invasive nature gave it an advantage on disturbed ground and, hence, it was often found in graveyards which is thought to have bound its association with death (21). <\/span><i><span style=\"font-weight: 400;\">V. minor<\/span><\/i><span style=\"font-weight: 400;\"> has a ground trailing habit (4)<\/span> <span style=\"font-weight: 400;\">. A bonus is that members of this genus are rarely troubled by browsing deer or rabbits. It spreads rapidly by long trailing and rooting stems once it is established and will swamp out smaller plants (13). <\/span><span style=\"font-weight: 400;\">G<\/span><span style=\"font-weight: 400;\">iven the chance, it will climb up though other plants that it uses for support as seen here situated on the roadside. <\/span>","sustainability":"<span style=\"font-weight: 400;\"><img class=\" wp-image-10530 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2023\/10\/09115149\/sustainability-icon-green.jpg\" alt=\"\" width=\"233\" height=\"232\" \/>Habitat loss and over-harvesting from the wild are two of the biggest threats faced by medicinal plant species. There are an increasing number of well-known herbal medicines at risk of extinction. We must therefore ensure that we source our medicines with sustainability in mind.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The herb supplement industry is growing at a rapid rate and until recent years a vast majority of medicinal plant produce in global trade was of unknown origin. There are some very real and urgent issues surrounding sustainability in the herb industry. These include environmental factors that affect the medicinal viability of herbs, the safety of the habitats that they are taken from, as well as the welfare of workers in the trade.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The botanical supply chain efforts for improved visibility (transparency and traceability) into verifiably sustainable production sites around the world is now certificated through the emergence of credible international voluntary sustainability standards (VSS).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality and safety: What to know before you buy <\/span><\/a><span style=\"font-weight: 400;\">and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"<span style=\"font-weight: 400;\">Herbal Medicines are often extremely safe to take, however it is important to buy herbal medicines from a reputed supplier. Sometimes herbs bought from unreputable sources are contaminated, adulterated or substituted with incorrect plant matter.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Some important markers for quality to look for would be to look for certified organic labelling, ensuring that the correct scientific\/botanical name is used and that suppliers can provide information about the source of ingredients used in the product.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">A supplier should be able to tell you where the herbs have come from. There is more space for contamination and adulteration when the supply chain is unknown.<\/span>","how_to_grow":"<span style=\"font-weight: 400;\">Plant established seedlings or small pot plants into their permanent positions in late spring or early summer, after the last expected frosts. Water regularly. A very easily grown plant, it succeeds in almost any soil but prefers those that are on the richer side. It grows well in heavy clay soils. Plants are very shade tolerant but they do not flower so well in deep shade. It can grow well under deciduous trees, and in such a position it can succeed in dry soils. Established plants are drought tolerant (13).<\/span>","recipe":"<span style=\"font-weight: 400;\">Only old anecdotal recipes like using the flowers in a syrup as a gentle laxative. See our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/home-herbalism\/making-medicines\/how-to-make-herbal-syrup\/\"><span style=\"font-weight: 400;\">how to make herbal syrups<\/span><\/a><span style=\"font-weight: 400;\"> to learn how to make this. <\/span>","references":"<ol>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">McIntyre, A, 2019. <\/span><i><span style=\"font-weight: 400\">The Complete Herbal Tutor<\/span><\/i><span style=\"font-weight: 400\">. Aeon Books. London, UK.<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Wood, M. 2008. <\/span><i><span style=\"font-weight: 400\">The Earthwise Herbal Volume 1: A complete guide to old world medicinal plants. <\/span><\/i><span style=\"font-weight: 400\">North Atlantic Books. Berkeley, California, U.S.A.<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> McIntyre, A, 2002. <\/span><i><span style=\"font-weight: 400\">The Complete Floral Healer<\/span><\/i><span style=\"font-weight: 400\">. Sterling Publishing. New York, U.S.A.<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Culpepper, N. 1814. <\/span><i><span style=\"font-weight: 400\">The Complete Herbal<\/span><\/i><span style=\"font-weight: 400\">. Accessed: https:\/\/archive.org\/details\/ cu31924001353279\/page\/n119\/mode\/2up Publisher: Richard Evans, Spitalfields, London.<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Gerard, J. 1597. <\/span><i><span style=\"font-weight: 400\">The General History if Plants. <\/span><\/i><span style=\"font-weight: 400\">Available at: https:\/\/www.exclassics.com\/herbal\/ herbalv3.pdf (Accessed: 11.07.2022).\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Grieve, M, 1931. <\/span><i><span style=\"font-weight: 400\">A Modern Herbal Vol II<\/span><\/i><span style=\"font-weight: 400\">. Stone Basin Books, USA.<\/span><span style=\"font-weight: 400\">\r\n<\/span><span style=\"font-weight: 400\">Grieve, M. 1931. <\/span><i><span style=\"font-weight: 400\">A Modern Herbal. <\/span><\/i><span style=\"font-weight: 400\">Available at: <\/span><a href=\"https:\/\/www.botanical.com\/botanical\/mgmh\/p\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400\">https:\/\/www.botanical.com\/botanical\/mgmh\/p\/<\/span><\/a><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Drugbank Online. 2022. <\/span><i><span style=\"font-weight: 400\">Vincamine<\/span><\/i><span style=\"font-weight: 400\">. Available at: <a href=\"https:\/\/go.drugbank.com\/drugs\/DB13374\" target=\"_blank\" rel=\"noopener\">https:\/\/go.drugbank.com\/drugs\/DB13374<\/a> (Accessed 18.01.2022).<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\"> Hong,Y., &amp; Yu-Hong, S. 2011<\/span><i><span style=\"font-weight: 400\">. Vincamine-producing endophytic fungus isolated from Vinca minor. <\/span><\/i><span style=\"font-weight: 400\">Available at: https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0944711311000067 (Accessed: 04.04.2022).<\/span><\/li>\r\n \t<li style=\"font-weight: 400\"><span style=\"font-weight: 400\">\u00a0Vrabek, R. et al. 2021. <\/span><i><span style=\"font-weight: 400\">Monoterpene indole alkaloids from Vinca minor L. 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Vinpocetine for cognitive impairment and dementia. <\/span><i><span style=\"font-weight: 400\">Cochrane Library<\/span><\/i><span style=\"font-weight: 400\">. 2003;2010(1). doi:10.1002\/14651858.cd003119<\/span><\/li>\r\n<\/ol>","related_condition":[11662,6956],"related_herb":[1922,1842],"related_article":[8911,12521],"herb_overview_content_one":"","herb_overview_content_two":"","herb_overview_content_three":"","herb_overview_content_four":"","herb_overview_content_five":"","herb_overview_content_six":"","herb_overview_content_seven":"","herb_overview_content_eight":"","botany":"","botanical_description":"","botanical_image":null,"common_names":"","herbal_preperation_image":null,"preparation":"","plant_part_used":"","dosage":"","constituents":"","recipe_image":null,"safety_post":null,"safety":"","interactions":"","contraindications":"","sustainability_image_one":null,"sustainability_image_two":null,"faqs":null,"not_suitable_for":[]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",1000,667,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor-600x400.jpg",600,400,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",580,387,false],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",1000,667,false],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2024\/08\/04104138\/Lesser-periwinkle-Vinca-minor.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 comments","_links":{"self":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/13270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb"}],"about":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/types\/herb"}],"version-history":[{"count":0,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/13270\/revisions"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/12521"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/8911"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/1842"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/1922"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/6956"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/11662"}],"acf:term":[{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/786"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/18"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/31"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media\/13275"}],"wp:attachment":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media?parent=13270"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/tags?post=13270"},{"taxonomy":"conditions","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/conditions?post=13270"},{"taxonomy":"sustainability","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sustainability?post=13270"},{"taxonomy":"sense","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense?post=13270"},{"taxonomy":"western_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/western_action?post=13270"},{"taxonomy":"chinese_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/chinese_action?post=13270"},{"taxonomy":"ayurvedic_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/ayurvedic_action?post=13270"},{"taxonomy":"energetics_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/energetics_action?post=13270"},{"taxonomy":"region","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/region?post=13270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}