{"id":2288,"date":"2020-08-12T13:12:46","date_gmt":"2020-08-12T12:12:46","guid":{"rendered":"https:\/\/www.herbalreality.com\/?post_type=herb&#038;p=2288"},"modified":"2025-09-20T11:06:49","modified_gmt":"2025-09-20T10:06:49","slug":"echinacea","status":"publish","type":"herb","link":"https:\/\/www.herbalreality.com\/herb\/echinacea\/","title":{"rendered":"Echinacea"},"content":{"rendered":"","protected":false},"featured_media":441,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"footnotes":"","beyondwords_generate_audio":"1","beyondwords_project_id":"47224","beyondwords_content_id":"a8c82c0e-1c6c-4d18-a1d9-8dbf4f48b8f1","beyondwords_preview_token":"4d066b67-3694-415d-a44f-bb38c05f722e","beyondwords_player_content":"","beyondwords_player_style":"","beyondwords_language_code":"","beyondwords_language_id":"","beyondwords_title_voice_id":"","beyondwords_body_voice_id":"","beyondwords_summary_voice_id":"","beyondwords_error_message":"","beyondwords_disabled":"","beyondwords_delete_content":"","beyondwords_podcast_id":"","beyondwords_hash":"","publish_post_to_speechkit":"","speechkit_hash":"","speechkit_generate_audio":"","speechkit_project_id":"","speechkit_podcast_id":"","speechkit_error_message":"","speechkit_disabled":"","speechkit_access_key":"","speechkit_error":"","speechkit_info":"","speechkit_response":"","speechkit_retries":"","speechkit_status":"","speechkit_updated_at":"","_speechkit_link":"","_speechkit_text":""},"tags":[213,212,54],"conditions":[695,701,700],"sustainability":[1575],"sense":[17,31,18,30],"western_action":[992,989,993,994,996,1001,1014,1015,1826,1025],"chinese_action":[],"ayurvedic_action":[],"energetics_action":[1498,1382,1487,1497,1492],"region":[1893],"class_list":["post-2288","herb","type-herb","status-publish","has-post-thumbnail","hentry","tag-colds","tag-echinacea","tag-flu","conditions-respiratory-system","conditions-immune-system","conditions-skin","sustainability-amber-sustainability-status","sense-aromatic","sense-astringent-taste","sense-bitter","sense-sharp","western_action-anti-inflammatory","western_action-alterative","western_action-antimicrobial","western_action-antioxidant","western_action-antirheumatic","western_action-bitter","western_action-hepatoprotective","western_action-immunomodulant","western_action-lymphatic","western_action-vulnerary","energetics_action-bitter","energetics_action-cool","energetics_action-dry","energetics_action-pungent","energetics_action-toning","region-western-herbs"],"acf":{"last_reviewed":"20240802","herb_author":1235,"banner_text":"Echinacea is most widely known for its use as an immune support","latin_name":"<em>Echinacea purpurea \/ E. angustifolia<\/em>","pseudonym_name":"","family_name":"Asteraceae","herb_summary":"During the early 20th century, echinacea was the most popular remedy in the USA for managing infections and was only eclipsed by the arrival of antibiotics after the Second World War.","key_benefits":"Prevention against upper respiratory infections\r\nPersistent and chronic infections\r\nWound healing\r\nAs a mouthwash","how_does_it_feel":"<span style=\"font-weight: 400;\">Echinacea remedies come in many different forms, with two dominant species (<\/span><i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\"> and <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\">), and sometimes a third (<\/span><i><span style=\"font-weight: 400;\">E. pallida<\/span><\/i><span style=\"font-weight: 400;\">). Other species are sometimes encountered, however there are significant levels of adulteration with completely different species. It is very important to first locate a reputable supplier with a good quality product. Then having been assured that the echinacea is of good quality there will still be a range of forms and tastes to encounter. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">In North American tradition the benchmark was provided by the root of <\/span><i><span style=\"font-weight: 400;\">echinacea angustifolia<\/span><\/i><span style=\"font-weight: 400;\">, as this has the strongest characteristic \u2018tingle\u2019 effect, but it is also harder to grow in commercial quantities. Particularly in Europe, the leaves and aerial parts of echinacea purpurea are most common; the root of that species is the most widely sold worldwide (1).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">To get the strongest impact try to obtain a product made from <\/span><i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\"> root. The effect of even a small taste is dramatic! The first impact is fiery, a quick very sharp astringency that covers all surfaces of the mouth, even the lips. Thereafter follows waves of sour and bitter tingling, and a very persistent long acrid, dry astringent aftertaste, leading to reflex increased salivation.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The aerial parts of <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\">\u00a0 have a more subtle taste, initially sweet, then some bitterness and a little tingling and astringency. The root of <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\"> will be somewhere in between.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The tingling effect is produced by alkylamides and the subtle sweetness by polysaccharides. Both have been implicated in helping to improve the body\u2019s defences (2,3).<\/span>","hdif_image_1":3301,"hdif_image_2":11326,"hdif_image_3":9052,"hdif_video":"https:\/\/youtu.be\/HxfaaJK4sGQ","sense":[17,31,18,30],"what_can_i_use_it_for":"[caption id=\"attachment_8779\" align=\"alignright\" width=\"425\"]<img class=\" wp-image-8779\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2022\/01\/21123249\/echinacea-angustifolia-600x600.jpeg\" alt=\"Echinacea (Echinacea angustifolia)\" width=\"425\" height=\"425\" \/> Echinacea (<em>Echinacea angustifolia<\/em>)[\/caption]\r\n\r\nEchinacea can be used as a preventative for those who are prone to upper respiratory problems like frequent <a href=\"https:\/\/www.herbalreality.com\/condition\/cold-and-flu\/\">colds<\/a>, sore throats, <a href=\"https:\/\/www.herbalreality.com\/condition\/sinusitis\/\">sinusitis<\/a>, middle ear pain, or viral infections like flu (2,3,4).\r\n\r\nEchinacea is the herbal practitioner\u2019s favourite for any infectious condition, where it is seen to support balanced immune responses, including moderating over-reactions (the idea that it could worsen autoimmune problems for example is based on a misunderstanding of its activity). Importantly however, infections should be treated with due respect and echinacea should not be a substitute for expert medical help. Consider it a great complement to frontline conventional treatments, becoming more important as more infections return or are resistant to standard antibiotic and other prescriptions (2,3,4).\r\n\r\nIt has local action in other areas, and forms brilliant mouthwash for any inflammation in the mouth, throat and gums. It is a useful remedy applied externally to boils, carbuncles and abscesses, and as a douche for vaginal infections (2,3,4).\r\n\r\nInto the heart of (<i>can include information like the energetics and essence of the plant<\/i>)\r\nEchinacea is best understood as defending from the outside in, supporting immune function and reducing inflammation and infection by mobilising defences on mucosal surfaces (5).\r\n\r\nIt contains constituents known as isobutylamides, which are types of alkylamides. They act as insecticide defences for the plant and are found particularly in the roots. They can be clearly identified through tasting good quality echinacea, as they create a \u2018tingling\u2019 or numbing effect upon the tongue. From laboratory studies it appears they may directly influence inflammatory cytokine production among defensive white blood cells found close to mucosal surfaces. Among other possible mechanisms they activate a type of cannabinoid receptor (CB2) that is involved in immune and inflammatory modulation (6,7).\r\n\r\nEchinacea is considered as one of the primary remedies for assisting the body in clearing infection and strengthening the overall efficiency of the immune system. Echinacea reduces the severity and duration of symptoms, whilst also helping the body to deal with infection and stimulate the immune response. It will effectively target microbial, bacterial and viral infections throughout the body, but has a specific focus within the upper respiratory system and in conditions such as cold and flu, tonsillitis and laryngitis (3,4,8).\r\n\r\nEchinacea is effective where the immune system has become compromised by being run-down as a result of <a href=\"https:\/\/www.herbalreality.com\/condition\/stress-and-relaxation\/\">stress<\/a> or over-work.","into_the_heart_of":"[caption id=\"attachment_3300\" align=\"alignright\" width=\"515\"]<img class=\" wp-image-3300\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/12\/21125505\/Echinacea-flower-field-600x400.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"515\" height=\"343\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Echinacea is best understood as defending from the outside in, supporting immune function and reducing inflammation and infection by mobilising defences on mucosal surfaces (5).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It contains constituents known as isobutylamides, which are types of alkylamides. They act as insecticide defences for the plant and are found particularly in the roots. They can be clearly identified through tasting good quality echinacea, as they create a \u2018tingling\u2019 or numbing effect upon the tongue. From laboratory studies it appears they may directly influence inflammatory cytokine production among defensive white blood cells found close to mucosal surfaces. Among other possible mechanisms they activate a type of cannabinoid receptor (CB2) that is involved in immune and inflammatory modulation (6,7).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Echinacea is considered as one of the primary remedies for assisting the body in clearing infection and strengthening the overall efficiency of the immune system. Echinacea reduces the severity and duration of symptoms, whilst also helping the body to deal with infection and stimulate the immune response. It will effectively target microbial, bacterial and viral infections throughout the body, but has a specific focus within the upper respiratory system and in conditions such as cold and flu, tonsillitis and laryngitis (3,4,8).<\/span><span style=\"font-weight: 400;\">Echinacea is effective where the immune system has become compromised by being run-down as a result of <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/stress-and-relaxation\/\"><span style=\"font-weight: 400;\">stress<\/span><\/a><span style=\"font-weight: 400;\"> or over-work.<\/span>","tradtional_uses":"[caption id=\"attachment_2867\" align=\"alignright\" width=\"512\"]<img class=\" wp-image-2867\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/10\/21125655\/dry-echinacea-tea-600x400.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"512\" height=\"341\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">The roots of echinacea come with a formidable reputation from the annals of the settler tradition in North America, with one writer M.R Gilmore observing the native population using it as a \u201cremedy for more ailments than any other plant\u201d. In particular, it was recommended for\u00a0 snake bites and other venomous creatures (to the extent that one researcher publicly volunteered to allow himself to be bitten by rattlesnakes to prove the point to his colleagues!). It is also used for infected and poisonous conditions generally, to treat burns and wounds, and for toothache and sore throats. Septic problems were widely treated with nothing more than echinacea, and most modern herbalists would go far to ensure a good supply (9,10).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The Native Americans and the 19th century Eclectic physicians who adopted their use of echinacea, preferred <\/span><i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\"> root. This type\u00a0 is high in alkylamides that impart a persistent tingling sensation in the mouth and stimulate the flow of saliva, long considered a sign of good quality (and likely to be a key part of its reputation) (1).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The worldwide reputation of echinacea was cemented when the German homoeopathic physician Dr Madaus visited the USA in the 1930\u2019s and observed that it was the most popular home remedy for infections across the country. Probably because of the difficulty of mass cultivation of e<\/span><i><span style=\"font-weight: 400;\">chinacea angustifolia<\/span><\/i><span style=\"font-weight: 400;\">, he created a new prescription medicine\u00a0 using the aerial parts of <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\"> (11).<\/span>","what_practioners_say":"<h3><span style=\"font-weight: 400;\"><img class=\" wp-image-6372 alignright\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2022\/02\/21124316\/Subcategory-Conditions-respiratory-system-600x600.jpg\" alt=\"Respiratory system\" width=\"387\" height=\"387\" \/>Respiratory system\u00a0<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">Echinacea is used to fend off tendencies to cold, flu, tonsillitis, pharyngitis, laryngitis, general mucous and sinus congestion. The immune stimulating and <\/span><a href=\"https:\/\/www.herbalreality.com\/western-action\/antimicrobial\/\"><span style=\"font-weight: 400;\">antimicrobial <\/span><\/a><span style=\"font-weight: 400;\">properties of echinacea are focussed on throat surfaces and immediately underlying lymphatic tissues, which is where most upper respiratory battles are waged (3,5). The most effective way to take echinacea for these conditions is at the first onset of symptoms, and every two hours thereafter. It can also be applied to more chronic conditions including chronic respiratory tract infections or whooping cough (3,5).\u00a0<\/span>\r\n<h3><span style=\"font-weight: 400;\">Immune system<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">Echinacea works mainly in innate immunity (rather than the acquired immunity of antibody production) and is appropriate for any acute and chronic infections, whether due to bacterial, viral, protozoal or other organisms. It is likely to be particularly effective in infections on or near accessible surfaces, including the upper gut wall, though has also been used to modulate immune responses including in moderating <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/allergic-reaction\/\"><span style=\"font-weight: 400;\">allergies<\/span><\/a><span style=\"font-weight: 400;\"> and hypersensitivity reactions (8). Its antifungal properties also indicate its use in the treatment of <\/span><i><span style=\"font-weight: 400;\">Candida <\/span><\/i><span style=\"font-weight: 400;\">and thrush.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Echinacea works by stimulating macrophages, natural killer (NK) cells and T and B lymphocyte activity. As a result, it can be applied in cases of chronic low immunity and repeated infections as well to support convalescence and recovery from post viral fatigue (12).<\/span>\r\n<h3><span style=\"font-weight: 400;\">External<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">Echinacea is especially effective as a mouthwash for gum disease where the tingle factor from the alkylamides is most valued. It has traditionally been used to bathe infected and open wounds, bites or poisonings, especially when healing is impaired. It has also been used for hot and irritated skin conditions such as <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/eczema\/\"><span style=\"font-weight: 400;\">eczema<\/span><\/a><span style=\"font-weight: 400;\"> and <\/span><a href=\"https:\/\/www.herbalreality.com\/condition\/psoriasis\/\"><span style=\"font-weight: 400;\">psoriasis<\/span><\/a><span style=\"font-weight: 400;\">, and as a douche for vaginal infections (4).<\/span>","research":"[caption id=\"attachment_205664\" align=\"alignright\" width=\"508\"]<img class=\" wp-image-205664\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/08\/20105101\/Echinacea-Echinacea-purpurea-1000x750.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"508\" height=\"381\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">In Europe, it is traditionally the aerial parts of <\/span><i><span style=\"font-weight: 400;\">Echinacea purpurea<\/span><\/i><span style=\"font-weight: 400;\"> which are used and the evidence base is largely linked to this version.\u00a0<\/span>\r\n<h3><span style=\"font-weight: 400;\">Echinacea for preventing and treating the common cold<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">This review was carried out to investigate whether echinacea preparations were effective in the treatment of the common cold. The search was conducted on randomised clinical trials from 1946 to 2013. A total of 24 double blind trials with 4631 participants met the inclusion criteria. The authors favoured the aerial parts of <\/span><i><span style=\"font-weight: 400;\">Echinacea purpurea<\/span><\/i><span style=\"font-weight: 400;\">: \u201cOur exploratory meta-analyses suggest that at least some echinacea preparations may reduce the relative risk of catching a cold by 10% to 20%\u201d, however the evidence was not robust enough to be deemed clinically relevant(11).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">This review points out a familiar complaint among reviewers of the evidence: that they could not well distinguish between echinacea products (11).\u00a0\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">An earlier, and more positive Cochrane review by some of the same authors had pointed in favour of <\/span><i><span style=\"font-weight: 400;\">Echinacea purpurea<\/span><\/i><span style=\"font-weight: 400;\"> aerial parts (14). However, a later meta-analysis by other reviewers also did not differentiate between echinacea preparations (13).<\/span>\r\n<h3><span style=\"font-weight: 400;\">Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">A double blind placebo controlled trial was carried out to identify whether a standardised echinacea formulation is effective in the prevention of respiratory and other symptoms associated with long-haul flights. A total of 175 adults took part. The participants were travelling from Australia, to America, Europe, or Africa for a period of 1\u20135 weeks on commercial flights via economy class.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The subjects were given echinacea (root extract, standardised to 4.4\u2009mg alkylamides) or placebo tablets. Participants were surveyed before, immediately after travel, and at four weeks after travel.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The study concluded that supplementation with standardised echinacea tablets, if taken before and during travel, may have preventive effects against respiratory tract infections and related symptoms during travel involving long-haul flights (15).<\/span>\r\n<h3><span style=\"font-weight: 400;\">Echinacea reduces antibiotic usage in children through respiratory tract infection prevention: A randomised, blinded, controlled clinical trial<\/span><\/h3>\r\n<span style=\"font-weight: 400;\">This randomised, blinded, controlled clinical trial investigated the efficacy of echinacea in preventing respiratory tract infections (RTIs) and secondary bacterial infections thereby reducing antibiotic usage in children. Echinaforce \u00ae junior tablets equivalent to 400 mg or vitamin C as control were given three times daily for prevention to children between 4\u201312 years old. The results showed children taking echinacea had fewer cold days (429) compared to those taking vitamin C (602) and also <\/span><span style=\"font-weight: 400;\">exhibited<\/span><span style=\"font-weight: 400;\"> fewer symptoms. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">Echinacea reduced RTI episodes by 32.5% and a reduction of 76.3% in children needing antibiotics. Adverse effects were fewer in the echinacea group than the vitamin C group. It concludes that echinacea is effective in preventing and reducing RTIs and the need for antibiotic use (16).\u00a0<\/span>","did_you_know":"<span style=\"font-weight: 400;\">The name \u2018echinacea\u2019 is derived from the Greek word \u2018echino\u2019 which means \u2018sea urchin\u2019 or \u2018hedgehog\u2019. This was chosen because it aptly described the spiny central disc of the echinacea flowers. Traditionally, echinacea was used in Native American medical traditions to treat snake bites and blood poisoning (17).<\/span>","additional_information_right":{"illustration":204336},"additional_information_left":{"botany":"<span style=\"font-weight: 400;\">Echinacea is a perennial plant that can grow to between 3\u20135 feet tall with a distinctive coneflower (hence its other name purple coneflower). The leaves are lance shaped, rough and haired, alternate which become smaller higher up the stem.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The flower heads are typically pink to purple in colour with a distinctive dome shaped central cone consisting of multiple small bisexual tubular flowers. Ray florets surround the cone and are often pink or purple in colour. The plants flower from early summer into autumn (22).<\/span>","common_names":"<ul>\r\n \t<li><span style=\"font-weight: 400;\">Echinacea<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Rudbeckia<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Snakeroot<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Broad-leaved purple cone flower<\/span><\/li>\r\n \t<li><span style=\"font-weight: 400;\">Narrow-leafed purple cone flower<\/span><\/li>\r\n<\/ul>","safety":"<span style=\"font-weight: 400;\">Safe for most people, although caution should be exercised with lactation, and asthma due to the potential for echinacea to modulate cytokines which could provoke an inflammatory response. It is recommended to consult a medical herbalist in these cases (3,4,18).\u00a0\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">In 2012 a warning was issued by the MHRA that as a precautionary measure the remedy echinacea should not be given to children under 12 years old, due to a small risk of a severe allergic reaction which outweighed any benefits (18). However, since this time there has been research demonstrating the significant benefits of echinacea for children in reducing RTI\u2019s and subsequent antibiotic use with minimal allergic reactions within the study group (19). This was based on a specific extract of echinacea, but suggests that unless there is a specific known allergy to this plant family then echinacea can have many benefits to children\u2019s immunity.<\/span>","interactions":"<span style=\"font-weight: 400;\">There is conflicting information about taking immunosuppressant drugs and echinacea together and as such it is advised to consult a medical herbalist for guidance if using this medication.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">It may also alter HIV medication. Echinacea could also increase the effects of caffeine through inhibiting its metabolism (3, 4, 20).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Echinacea could also interact with cytochrome P450\u00a0 medication (3, 4, 20).<\/span>","contraindications":"<span style=\"font-weight: 400;\">Contraindicated in transplant patients taking immunosuppressants and those with a known allergy to Asteraceae family (3, 4, 20). <\/span>","preparation":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tincture<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Decoction<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Capsule<\/span><\/li>\r\n<\/ul>","dosage":"<ul>\r\n \t<li><span style=\"font-weight: 400;\"><strong>Tincture (1:5 45%):<\/strong> Take between 1\u20134 ml in a little water three times daily.<\/span><\/li>\r\n \t<li><strong>Decoction:<\/strong> To make a decoction, place 1\u20132 teaspoons of echinacea root into one cup of water and bring slowly to the boil. Simmer for around 15\u201320 minutes. Strain and drink up to three times daily (2, 12).<\/li>\r\n<\/ul>","constituents":"<ul>\r\n \t<li><strong>Alkylamides (alkamides):<\/strong> Isobutylamides<\/li>\r\n \t<li><strong>Caffeic acid derivatives:<\/strong> Echinacoside and cynarin (E. angustifolia); chicoric acid (E. purpurea), caftaric acid, cholorogenic acid and caffeic acid<\/li>\r\n \t<li><strong>Polysaccharides:<\/strong> Arabinogalactan-protein rich in hydroxyproline and heteroxylan, \u2018echinacin\u2019 (although identification and consistency of various polysaccharides is not clear)<\/li>\r\n \t<li><strong>Polyacetylenes:<\/strong> Echinalone in (E. purpurea), ketoalkenes, ketoalkynes<\/li>\r\n \t<li><strong>Essential oil<\/strong> (trace)<\/li>\r\n \t<li><strong>Resin\u00a0<\/strong><\/li>\r\n \t<li><strong>Betaine\u00a0<\/strong><\/li>\r\n \t<li><strong>Vitamins:<\/strong> A, C and E (2)<\/li>\r\n<\/ul>\r\nOf these constituents there is evidence for immunological activity of the polysaccharides, though as these are quickly broken down on digestion such activity will be confined to surface defences in the mouth and throat. Most interest recently has been in the activity of the alkylamides, in modulating the activity of cannabinoid receptors (CB2) which have <a href=\"https:\/\/www.herbalreality.com\/western-action\/immunomodulant\/\"><span style=\"font-weight: 400;\">immune-modulating<\/span><\/a><span style=\"font-weight: 400;\"> activity. <\/span>\r\n\r\n<span style=\"font-weight: 400;\">The alkylamides, especially the isobutylamides have a characteristic tingling effect in the mouth and have long been considered a mark of quality of echinacea and are particularly prominent in <\/span><i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\">. Caffeic acid derivatives from the latter have also shown antihyaluronidase activity: hyaluronidase is an enzyme that some infective bacteria use to penetrate mucosal surfaces (1, 2, 21).<\/span>","plant_part_used":"<ul>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Root\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aerial parts <\/span><\/li>\r\n<\/ul>"},"habitat":"<span style=\"font-weight: 400;\">Both species are native to eastern and central North America where they commonly grow in moist to dry woodlands or prairies. This plant is now cultivated across the globe for both medicinal and horticultural purposes. <\/span><i><span style=\"font-weight: 400;\">Echinacea angustifolia<\/span><\/i><span style=\"font-weight: 400;\"> is threatened in the wild and harder to grow than <\/span><i><span style=\"font-weight: 400;\">E. purpurea <\/span><\/i><span style=\"font-weight: 400;\">(23). <\/span>","sustainability":"[caption id=\"attachment_97188\" align=\"alignright\" width=\"414\"]<a href=\"https:\/\/www.herbalreality.com\/herbalism\/sustainability-social-welfare\/herb-species-sustainability-guide\/\"><img class=\" wp-image-97188\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2025\/05\/25101353\/Amber-sustainability-status-1000x1000.png\" alt=\"Amber Sustainability Status\" width=\"414\" height=\"414\" \/><\/a> At risk from overharvesting and habitat loss. Read more in our\u00a0<a href=\"https:\/\/www.herbalreality.com\/herbalism\/sustainability-social-welfare\/herb-species-sustainability-guide\/\">sustainability guide<\/a>.[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">Natureserve states that the echinacea species are apparently secure although borderline vulnerable. <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\"> is observed to have a fairly patchy distribution in its native habitats across the US with only small and sporadic populations. Habitat loss is a problem for this plant (24,25).<\/span>\r\n\r\n<i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\">, although still abundant, has suffered nearly a century of wild root harvesting across the range. Other threats include the destruction of its native prairie habitat by converting it to pastures and highway maintenance practices (26,27).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Habitat loss and over-harvesting from the wild are two of the biggest threats faced by medicinal plant species. There are an increasing number of well-known herbal medicines at risk of extinction. We must, therefore, ensure that we source our medicines with sustainability in mind.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The herb supplement industry is growing at a rapid rate and until recent years a vast majority of medicinal plant produce in global trade was of unknown origin. There are some very real and urgent issues surrounding sustainability in the herb industry. These include environmental factors that affect the medicinal viability of herbs, the safety of the habitats that they are taken from, as well as the welfare of workers in the trade.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">The botanical supply chain efforts for improved visibility (transparency and traceability) into verifiably sustainable production sites around the world is now certificated through the emergence of credible international voluntary sustainability standards (VSS).<\/span><span style=\"font-weight: 400;\">\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Read our article on <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/safety\/herbal-quality-safety-what-know-before-you-buy\/\"><span style=\"font-weight: 400;\">Herbal quality &amp; safety: What to know before you buy<\/span><\/a><span style=\"font-weight: 400;\">\u00a0and <\/span><a href=\"https:\/\/www.herbalreality.com\/herbalism\/western-herbal-medicine\/where-your-herbs-come-from\/\"><span style=\"font-weight: 400;\">Sustainable sourcing of herbs<\/span><\/a><span style=\"font-weight: 400;\"> to learn more about what to look for and questions to ask suppliers about sustainability.<\/span>","sustainability_content":"","sustainability_alternatives":"","quality_control":"[caption id=\"attachment_205669\" align=\"alignright\" width=\"513\"]<img class=\" wp-image-205669\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/08\/20110223\/Echinacea-Echinacea-purpurea-1-1000x666.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"513\" height=\"342\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">There are three species of echinacea that are pharmaceutically important. <\/span><i><span style=\"font-weight: 400;\">Echinacea angustifolia<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><i><span style=\"font-weight: 400;\">E. pallida<\/span><\/i><span style=\"font-weight: 400;\"> and <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\">. The compounds are similar across all three species but there are variations in the specific metabolites (28).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">National pharmacopoeias have separate monographs for each of the species which set minimum levels for certain compounds. The British Pharmacopoeia (BP) has a monograph for the roots of <\/span><i><span style=\"font-weight: 400;\">E. pallida<\/span><\/i><span style=\"font-weight: 400;\"> and <\/span><i><span style=\"font-weight: 400;\">E. angustifolia<\/span><\/i><span style=\"font-weight: 400;\"> setting a level of echinacoside at 0.2% and 0.5%, respectively. There is a monograph for both the leaves and roots of <\/span><i><span style=\"font-weight: 400;\">E. purpurea<\/span><\/i><span style=\"font-weight: 400;\">, with a minimum level for caftaric and cichoric acid of 0.5% in the leaf and 0.1% in the root (29).<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Adulteration with other plant species has been observed in echinacea, but recent studies show that the undeclared use of other echinacea species or plant parts is a more common occurrence. It is not always clear if echinacea adulteration is done on purpose or accidental, as species confusion are known from this genus (30).\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Fortunately, there are techniques available that can help identify these forms of adulteration. These include high performance thin layer chromatography (HPTLC) in which the presence of different constituents and the concentration can enable the species to be distinguished. The plant parts can also be differentiated through this technique, as chlorophyll pigments will only be present in the leaves.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Herbal medicines are often very safe to take, however, it is important to buy herbal medicines from a reputed supplier. Sometimes herbs bought from disreputable sources are contaminated, adulterated or substituted with incorrect plant matter.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Some important markers for quality to look for would be to look for certified organic labelling, ensuring that the correct scientific\/botanical name is used and that suppliers can provide information about the source of ingredients used in the product.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">A supplier should be able to tell you where the herbs have come from. There is more space for contamination and adulteration when the supply chain is unknown.<\/span>","how_to_grow":"[caption id=\"attachment_205670\" align=\"alignright\" width=\"512\"]<img class=\" wp-image-205670\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/08\/20110225\/Echinacea-cone-Echinacea-purpurea-1000x666.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"512\" height=\"341\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n\r\n<span style=\"font-weight: 400;\">The easiest method for sowing echinacea is to sow it indoors in trays (open trays or plugs) in early spring. Sow the seeds on the surface, or with a very light covering of seed compost, keep moist, and you should start to see germination within 1\u20132 weeks.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">There are different opinions on whether echinacea seeds should be stratified before sowing. Following experimentation, the best results were found by cold-moist stratification (mixed with sand, put in a sealed bag and kept in the fridge) for 1\u20133 months. This method resulted in quicker germination than non-stratified seed, and with a slightly higher germination rate.\u00a0<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Sowing outdoors in the autumn can mean a longer germination time, with a lower germination rate. These outdoor seedlings, although harder to germinate and slower to grow, do appear to be more robust than their indoor counterparts \u2013 perhaps an important advantage if your garden is prone to slugs, frost or any other threats to survival.<\/span>\r\n\r\n<span style=\"font-weight: 400;\">Transplant into the final position as early as possible with a spacing of around 30\u201360 cm. If you\u2019re lucky you may get a few flowers in the first year. And in the second year you\u2019re in for a special treat (31)!\u00a0<\/span>","recipe":"<h3>Elderberry and echinacea winter warmer tea<\/h3>\r\nThis elderberry and echinacea winter warmer tea targets the cause of seasonal infections by strengthening both short- and long-term immunity.\r\n\r\n[caption id=\"attachment_2867\" align=\"alignright\" width=\"512\"]<img class=\" wp-image-2867\" src=\"https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/10\/21125655\/dry-echinacea-tea-scaled.jpg\" alt=\"Echinacea (Echinacea purpurea)\" width=\"512\" height=\"341\" \/> Echinacea (<em>Echinacea purpurea<\/em>)[\/caption]\r\n<h4>Ingredients<\/h4>\r\n<ul>\r\n \t<li>Echinacea root 2 g<\/li>\r\n \t<li>Elderberry 2 g<\/li>\r\n \t<li>Elderflower 2 g<\/li>\r\n \t<li>Rosehip 2 g<\/li>\r\n \t<li>Peppermint leaf 2 g<\/li>\r\n \t<li>Orange peel 2 g<\/li>\r\n \t<li>Aniseed 1 g<\/li>\r\n \t<li>Ginger root powder 1 g<\/li>\r\n \t<li>Licorice root 1 g<\/li>\r\n \t<li>Orange essential oil a drop per cup<\/li>\r\n<\/ul>\r\n<h4>Method<\/h4>\r\n<ol>\r\n \t<li>Put all of the ingredients (except for the orange essential oil) in a pot.<\/li>\r\n \t<li>Add 500ml\/18fl oz freshly boiled filtered water.<\/li>\r\n \t<li>Leave to steep for 10\u201315 minutes, then strain.<\/li>\r\n \t<li>Add a drop of orange essential oil to each cup.<\/li>\r\n<\/ol>\r\nThis will serve 2-3 cups of good health.\r\n\r\nThis recipe is from the book\u00a0<a href=\"https:\/\/www.amazon.co.uk\/Cleanse-Nurture-Restore-Herbal-Tea\/dp\/0711238294\/\" target=\"_blank\" rel=\"noopener\">Cleanse, Nurture, Restore<\/a>\u00a0by Sebastian Pole","references":"<ol>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">American Botanical Council (ABC). Expanded Commission E: Echinacea Angustifolia herb and root\/Pallida herb. cms.herbalgram.org. Accessed August 2, 2024. <\/span><a href=\"http:\/\/cms.herbalgram.org\/expandedE\/EchinaceaAngustifoliaherbandrootPallidaherb.html\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">http:\/\/cms.herbalgram.org\/expandedE\/EchinaceaAngustifoliaherbandrootPallidaherb.html<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fisher C. <\/span><i><span style=\"font-weight: 400;\">Materia Medica of Western Herbs<\/span><\/i><span style=\"font-weight: 400;\">. Aeon Books; 2018.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Thomsen M. <\/span><i><span style=\"font-weight: 400;\">Phytotherapy Desk Reference.<\/span><\/i><span style=\"font-weight: 400;\"> 6th ed. Aeon Books; 2022.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mcintyre A. <\/span><i><span style=\"font-weight: 400;\">Complete Herbal Tutor : The Definitive Guide to the Principles and Practices of Herbal Medicine (Second Edition).<\/span><\/i><span style=\"font-weight: 400;\"> Aeon Books Limited; 2019.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hall H, Fahlman M, Engels H. Echinacea Purpurea and Mucosal Immunity. <\/span><i><span style=\"font-weight: 400;\">International Journal of Sports Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2007;28(9):792-797. <\/span><a href=\"https:\/\/doi.org\/10.1055\/s-2007-964895\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1055\/s-2007-964895<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Mudge E, Lopes-Lutz D, Brown P, Schieber A. Analysis of Alkylamides in Echinacea Plant Materials and Dietary Supplements by Ultrafast Liquid Chromatography with Diode Array and Mass Spectrometric Detection. <\/span><i><span style=\"font-weight: 400;\">Journal of Agricultural and Food Chemistry<\/span><\/i><span style=\"font-weight: 400;\">. 2011;59(15):8086-8094. <\/span><a href=\"https:\/\/doi.org\/10.1021\/jf201158k\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1021\/jf201158k<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Elufioye TO, Habtemariam S, Adejare A. Chemistry and Pharmacology of Alkylamides from Natural Origin. <\/span><i><span style=\"font-weight: 400;\">Revista Brasileira de Farmacognosia<\/span><\/i><span style=\"font-weight: 400;\">. 2020;30(5):622-640. <\/span><a href=\"https:\/\/doi.org\/10.1007\/s43450-020-00095-5\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1007\/s43450-020-00095-5<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Zhai Z, Liu Y, Wu L, et al. Enhancement of Innate and Adaptive Immune Functions by Multiple Echinacea Species. <\/span><i><span style=\"font-weight: 400;\">Journal of Medicinal Food<\/span><\/i><span style=\"font-weight: 400;\">. 2007;10(3):423-434. <\/span><a href=\"https:\/\/doi.org\/10.1089\/jmf.2006.257\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1089\/jmf.2006.257<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">BHMA. Echinacea | British Herbal Medicine Association. British Herbal Medicine Association. Accessed August 2, 2024. <\/span><a href=\"https:\/\/bhma.info\/indications\/coughs-colds-flu\/echinacea\/#:~:text=Echinacea%20was%20used%20for%20centuries\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/bhma.info\/indications\/coughs-colds-flu\/echinacea\/#:~:text=Echinacea%20was%20used%20for%20centuries<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Hostettmann K. [History of a plant: the example of Echinacea]. <\/span><i><span style=\"font-weight: 400;\">Forschende Komplementarmedizin Und Klassische Naturheilkunde = Research in Complementary and Natural Classical Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2003;10 Suppl 1(10):9-12. <\/span><a href=\"https:\/\/doi.org\/10.1159\/000071678\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1159\/000071678<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Karsch-V\u00f6lk M, Barrett B, Kiefer D, Bauer R, Ardjomand-Woelkart K, Linde K. Echinacea for preventing and treating the common cold. <\/span><i><span style=\"font-weight: 400;\">Cochrane Database of Systematic Reviews<\/span><\/i><span style=\"font-weight: 400;\">. 2014;(2). <\/span><a href=\"https:\/\/doi.org\/10.1002\/14651858.cd000530.pub3\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1002\/14651858.cd000530.pub3<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bone K, Mills S. <\/span><i><span style=\"font-weight: 400;\">Principles and Practice of Phytotherapy: Modern Herbal Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2nd ed. Edinburgh Churchill Livingstone, Elsevier; 2013.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Linde K, Barrett B, Bauer R, Melchart D, Woelkart K. Echinacea for preventing and treating the common cold. Linde K, ed. <\/span><i><span style=\"font-weight: 400;\">Cochrane Database of Systematic Reviews<\/span><\/i><span style=\"font-weight: 400;\">. Published online January 25, 2006. <\/span><a href=\"https:\/\/doi.org\/10.1002\/14651858.cd000530.pub2\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1002\/14651858.cd000530.pub2<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">David S, Cunningham R. Echinacea for the prevention and treatment of upper respiratory tract infections: A systematic review and meta-analysis. <\/span><i><span style=\"font-weight: 400;\">Complementary Therapies in Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2019;44:18-26. <\/span><a href=\"https:\/\/doi.org\/10.1016\/j.ctim.2019.03.011\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1016\/j.ctim.2019.03.011<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Tiralongo E, Lea RA, Wee SS, Hanna MM, Griffiths LR. Randomised, Double Blind, Placebo-Controlled Trial ofEchinaceaSupplementation in Air Travellers. <\/span><i><span style=\"font-weight: 400;\">Evidence-Based Complementary and Alternative Medicine<\/span><\/i><span style=\"font-weight: 400;\">. 2012;2012:1-9. <\/span><a href=\"https:\/\/doi.org\/10.1155\/2012\/417267\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1155\/2012\/417267<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Ogal M, Johnston SL, Klein P, Schoop R. Echinacea reduces antibiotic usage in children through respiratory tract infection prevention: a randomized, blinded, controlled clinical trial. <\/span><i><span style=\"font-weight: 400;\">European Journal of Medical Research<\/span><\/i><span style=\"font-weight: 400;\">. 2021;26(1). <\/span><a href=\"https:\/\/doi.org\/10.1186\/s40001-021-00499-6\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1186\/s40001-021-00499-6<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Grieve M. <\/span><i><span style=\"font-weight: 400;\">A Modern Herbal<\/span><\/i><span style=\"font-weight: 400;\">.; 1984.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Pizzorno JE, Murray MT, Joiner-Bey H. <\/span><i><span style=\"font-weight: 400;\">The Clinician\u2019s Handbook of Natural Medicine<\/span><\/i><span style=\"font-weight: 400;\">. Churchill Livingstone; 2016.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">De Filippis F, Paparo L, Nocerino R, et al. Specific gut microbiome signatures and the associated pro-inflamatory functions are linked to pediatric allergy and acquisition of immune tolerance. <\/span><i><span style=\"font-weight: 400;\">Nature Communications<\/span><\/i><span style=\"font-weight: 400;\">. 2021;12(1):5958. <\/span><a href=\"https:\/\/doi.org\/10.1038\/s41467-021-26266-z\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1038\/s41467-021-26266-z<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Natural Medicines. Echinacea. naturalmedicines.therapeuticresearch.com. Published 2024. <\/span><a href=\"https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/naturalmedicines.therapeuticresearch.com\/databases\/food<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Gertsch J. Immunomodulatory lipids in plants: plant fatty acid amides and the human endocannabinoid system. <\/span><i><span style=\"font-weight: 400;\">Planta medica<\/span><\/i><span style=\"font-weight: 400;\">. 2008;74(6):638-650. <\/span><a href=\"https:\/\/doi.org\/10.1055\/s-2008-1034302\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1055\/s-2008-1034302<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">RHS. Echinacea purpurea | purple coneflower Herbaceous Perennial\/RHS Gardening. www.rhs.org.uk. Published 2024. <\/span><a href=\"https:\/\/www.rhs.org.uk\/plants\/41568\/echinacea-purpurea\/details\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.rhs.org.uk\/plants\/41568\/echinacea-purpurea\/details<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Lim TK. Echinacea purpurea. <\/span><i><span style=\"font-weight: 400;\">Edible Medicinal And Non-Medicinal Plants<\/span><\/i><span style=\"font-weight: 400;\">. Published online September 3, 2013:340-371. <\/span><a href=\"https:\/\/doi.org\/10.1007\/978-94-007-7395-0_23\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1007\/978-94-007-7395-0_23<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NatureServe. Echinacea Purpurea. explorer.natureserve.org. Published 2024. <\/span><a href=\"https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.132226\/Echinacea_purpurea\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.132226\/Echinacea_purpurea<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Reinier J, Kirchner W, Preston JD, Meredith C. IUCN Red List of Threatened Species: Echinacea purpurea. IUCN Red List of Threatened Species. Published April 19, 2023. Accessed August 2, 2024. <\/span><a href=\"https:\/\/www.iucnredlist.org\/species\/88323256\/88323259\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/www.iucnredlist.org\/species\/88323256\/88323259<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">United Plant Savers. Echinacea \u2013 Echinacea spp. - United Plant Savers. United Plant Savers. Published August 28, 2019. <\/span><a href=\"https:\/\/unitedplantsavers.org\/echinacea-echinacea-spp-2\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/unitedplantsavers.org\/echinacea-echinacea-spp-2\/<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">NatureServe. Echinacea angustifolia. explorer.natureserve.org. Published 2024. <\/span><a href=\"https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.128470\/Echinacea_angustifolia\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/explorer.natureserve.org\/Taxon\/ELEMENT_GLOBAL.2.128470\/Echinacea_angustifolia<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Edward Trease G, Charles Evans W, Evans D. <\/span><i><span style=\"font-weight: 400;\">Trease and Evans Pharmacognosy<\/span><\/i><span style=\"font-weight: 400;\">. Saunders; 2009.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">British Pharmacopoeia Commission. <\/span><i><span style=\"font-weight: 400;\">British Pharmacopoeia 2025<\/span><\/i><span style=\"font-weight: 400;\">. London TSO; 2025.<\/span><\/li>\r\n \t<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Orhan N, Gafner S, Blumenthal M. Estimating the extent of adulteration of the popular herbs black cohosh, echinacea, elder berry, ginkgo, and turmeric \u2013 its challenges and limitations. <\/span><i><span style=\"font-weight: 400;\">Natural Product Reports<\/span><\/i><span style=\"font-weight: 400;\">. Published online January 1, 2024. <\/span><a href=\"https:\/\/doi.org\/10.1039\/d4np00014e\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/doi.org\/10.1039\/d4np00014e<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\r\n \t<li>Earthsong seeds. Echinacea angustifolia. Earthsong Seeds. Accessed August 2, 2024. <a href=\"https:\/\/earthsongseeds.co.uk\/shop\/herbs\/echinacea-angustifolia\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">https:\/\/earthsongseeds.co.uk\/shop\/herbs\/echinacea-angustifolia\/<\/span><\/a><\/li>\r\n<\/ol>","related_condition":[49,7880],"related_herb":[6231,1922],"related_article":[6267,6725],"herb_overview_content_one":"","herb_overview_content_two":"","herb_overview_content_three":"","herb_overview_content_four":"","herb_overview_content_five":"","herb_overview_content_six":"","herb_overview_content_seven":"","herb_overview_content_eight":"","botany":"","botanical_description":"","botanical_image":"","common_names":"Ingwer (Ger), gingembre (Fr), zenzero (Ital), jenjibre (Sp), adrakh, sont (Hindi), vishwabhesaja (Sanskrit), jiang (Chin). ","herbal_preperation_image":"","preparation":"","plant_part_used":"","dosage":"","constituents":"","recipe_image":"","safety_post":"","safety":"","interactions":"","contraindications":"","sustainability_image_one":"","sustainability_image_two":"","faqs":null,"not_suitable_for":[]},"featured_image_urls_v2":{"full":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10.jpg",1600,1067,false],"thumbnail":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10-600x600.jpg",600,600,true],"medium":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10-1000x667.jpg",1000,667,true],"large":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10-1300x867.jpg",580,387,true],"banner_image":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10-1600x800.jpg",1600,800,true],"gform-image-choice-sm":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10.jpg",300,200,false],"gform-image-choice-md":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10.jpg",400,267,false],"gform-image-choice-lg":["https:\/\/i.herbalreality.com\/wp-content\/uploads\/2020\/07\/21130530\/140904-echinacea-ohtc-10.jpg",600,400,false]},"post_excerpt_stackable_v2":"","category_list_v2":"","author_info_v2":{"name":"","url":""},"comments_num_v2":"0 comments","_links":{"self":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/2288","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb"}],"about":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/types\/herb"}],"version-history":[{"count":0,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/2288\/revisions"}],"acf:post":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/6725"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/posts\/6267"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/1922"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/herb\/6231"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/7880"},{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/condition\/49"}],"acf:term":[{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/30"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/18"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/31"},{"embeddable":true,"taxonomy":"sense","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense\/17"},{"embeddable":true,"taxonomy":"writer","href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/writer\/1235"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media\/441"}],"wp:attachment":[{"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/media?parent=2288"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/tags?post=2288"},{"taxonomy":"conditions","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/conditions?post=2288"},{"taxonomy":"sustainability","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sustainability?post=2288"},{"taxonomy":"sense","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/sense?post=2288"},{"taxonomy":"western_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/western_action?post=2288"},{"taxonomy":"chinese_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/chinese_action?post=2288"},{"taxonomy":"ayurvedic_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/ayurvedic_action?post=2288"},{"taxonomy":"energetics_action","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/energetics_action?post=2288"},{"taxonomy":"region","embeddable":true,"href":"https:\/\/www.herbalreality.com\/wp-json\/wp\/v2\/region?post=2288"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}